925691-15-2

Upstream product

• 626-62-0 Cyclohexyl iodide 
• 780-25-6 N-benzylidene benzylamine 
• 3376-26-9 N-Benzylidenebenzylamine N-oxide 
• 108-85-0 1-bromocyclohexane 
• 626606-89-1 N-(1-cyclohexyl-1-phenyl)methyl benzenecarbothioamide 
• 100-52-7 benzaldehyde 
• 100-46-9 benzylamine 
• 14309-89-8 N-benzyl-benzenecarbothioamide 

Relevant academic research and scientific papers

Indium (Zinc)-copper-mediated barbier-type alkylation reaction of nitrones in water: Synthesis of amines and hydroxylamines

An efficient method for the Barbier-type alkylation reaction of various nitrones (including chiral version) and alkyl halides in water is described. The amines and hydroxylamines can be obtained in good yields, depending on the judicious choice of the metal complexes used.

Indium-silver- and zinc-silver-mediated barbier-grignard-type alkylation reactions of imines by using unactivated alkyl halides in aqueous media

In the presence of In or Zn/AgI/InCl3, an efficient and practical method for the Barbier-Grignard-type alkylation reactions of simple imines by using a one-pot condensation of various aldehydes, amines (including the aliphatic and chiral version), and secondary alkyl iodides has been developed. The reaction proceeded more efficiently in water than in organic solvents. Without the use of CuI, it mainly gave the imine self-reductive coupling product, which was not the alkylated product. Good diastereoselectivities (up to 92:8 dr) were obtained when L-valine methyl ester was used as the substrate.

Indium - Copper-mediated barbier - Grignard-type alkylation reaction of imines in aqueous media

An efficient system of In/Cul/InCl3 was developed for Barbier-Grignard-type alkylation reactions of simple imines, using a one-pot condensation of various aldehydes, amines (including aliphatic and chiral version), and alkyl iodides in water or

Synthesis of 1,1′-binaphthyl-2,2′-diyl phosphoroselenoic amides and their conversion to optically pure phosphoramidites

Optically pure phosphoroselenoyl chloride was reacted with racemic amines to give phosphoroselenoic amides as two diastereomeric mixtures in high yields. The diastereomeric mixtures were separated by fractional recrystallization or by chromatography. Extr