92587-60-5

Upstream product

• 75-21-8 oxirane 
• 20472-52-0 iodo-diphenyl-phosphine 
• 4559-70-0 Diphenylphosphine oxide 
• 1079-66-9 chloro-diphenylphosphine 
• 68-12-2 N,N-dimethyl-formamide 
• 1499-21-4 Diphenylphosphinic chloride 
• 19115-01-6 potassium diphenylphosphide 

Downstream Products

• 56372-47-5 N,N-diethyl P,P-diphenylphosphinamide 
• 19833-78-4 di-ethylamine hydroiodide 
• 1706-96-3 phenyl diphenylphosphinate 

Relevant academic research and scientific papers

I2-Catalyzed Oxidative Coupling of Ketone Oximes and Dialkyl/Diarylphosphine Oxides

A new protocol for the oxidative coupling of ketone oximes with dialkyl/diarylphosphine oxides to synthesize O -(dialkylphosphinyl)ketone oximes has been developed. Hydrogen peroxide is used as a green oxidizing agent, and molecular iodine is used as a nonmetal catalyst. The reaction has a high atom economy, with water as the only byproduct. O -(Dialkylphosphinyl)ketone oximes with 26 examples have been obtained with high yields. Furthermore, the product may be transformed into other molecules, i.e., by reduction.

Highly regioselective hydroiodination of terminal alkynes and silylalkynes with iodine and phosphorus reagents leading to internal iodoalkenes

Markovnikov-type hydroiodination of terminal alkynes with iodine and Ph2P(O)H took place selectively to afford the corresponding internal iodoalkenes in good yields. Combination of (PhO)2P(O)H and Ph 2P(O)OH instead of Ph2P(O)H also provided internal iodoalkenes in excellent yields. This hydroiodination is advantageous in terms of mild conditions, convenient operation, and tolerance to various functional groups. In addition, direct synthesis of internal iodoalkenes from silylalkynes was also achieved by using a mixed system of iodine and phosphorus reagents.

Highly selective hydroiodation of alkynes using an iodine-hydrophosphine binary system

Figure presented A novel hydroiodation of alkynes (1) using an iodine/hydrophosphine binary system takes place regioselectively to provide the corresponding Markovnikov-type adducts (2) in good yield. This hydroiodation is advantageous in terms of mild conditions, convenient operation, and tolerance to various functional groups.

Stoichiometry of the reaction of diphenylchlorophosphine with dimethylformamide in the presence of NaI

Stoichiometric relations of initial compounds and reaction products in the synthesis of N,N-dialkyl-(diphenylphosphinomethylene)iminium are established; the second reaction product is diphenylphosphinic iodide. Bringing triphenylphosphine into the reaction increases the N,N- dialkyl(diphenylphosphinomethylene)-iminium yield approximately twice. One of the reaction intermediates is shown to be iododiphenylphosphine. The reaction can be regarded as disproportionation.

New approaches to the synthesis of diphosphine dioxides and hypophosphoric acid esters

An union >P-O- has been applied as an efficient synthetic precursor of four coordination compounds of the R2P(O)-(O)PR 2 type, namely diphosphine dioxides (R = alkyl, aryl) as well as hypophosphoric acid esters (R = alkoxy, aryloxy), in a one-pot reaction. Furthermore, there were elaborated some mechanistic aspects of the origin of the >P(O)-O-(O)PP-O- and >P(O)X (X= Cl, Br) electrophiles. Attention is focused on the synthesis of the >P(O)-(O)P compounds.