20472-52-0Relevant articles and documents
Facile, Catalytic Dehydrocoupling of Phosphines Using β-Diketiminate Iron(II) Complexes
King, Andrew K.,Buchard, Antoine,Mahon, Mary F.,Webster, Ruth L.
, p. 15960 - 15963 (2015/11/03)
Catalytic dehydrocoupling of primary and secondary phosphines has been achieved for the first time using an iron pre-catalyst. The reaction proceeds under mild reaction conditions and is successful with a range of diarylphosphines. A proton acceptor is not needed for the transformation to take place, but addition of 1-hexene does allow for turnover at 50°C. The catalytic system developed also facilitates the dehydrocoupling of phenylphosphane and dicyclohexylphosphane. A change in solvent switches off dehydrocoupling to allow hydrophosphination of alkenes.
Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor
Patnaik, Samarjit,Marugan, Juan J.,Liu, Ke,Zheng, Wei,Southall, Noel,Dehdashti, Seameen J.,Thorsell, Annika,Heilig, Markus,Bell, Lauren,Zook, Michelle,Eskay, Bob,Brimacombe, Kyle R.,Austin, Christopher P.
, p. 9045 - 9056 (2014/01/06)
The discovery and characterization of a novel chemical series of phosphorothioyl-containing imidazopyridines as potent neuropeptide S receptor antagonists is presented. The synthesis of analogues and their structure-activity relationship with respect to the Gq, Gs, and ERK pathways is detailed. The pharmacokinetics and in vivo efficacy of a potent analogue in a food intake rodent model are also included, underscoring its potential therapeutic value for the treatment of sleep, anxiety, and addiction disorders. This article not subject to U.S. Copyright. Published 2013 by the American Chemical Society.
Stoichiometry of the reaction of diphenylchlorophosphine with dimethylformamide in the presence of NaI
Morgalyuk,Petrovskii,Lysenko,Nifant'Ev
experimental part, p. 100 - 105 (2010/05/01)
Stoichiometric relations of initial compounds and reaction products in the synthesis of N,N-dialkyl-(diphenylphosphinomethylene)iminium are established; the second reaction product is diphenylphosphinic iodide. Bringing triphenylphosphine into the reaction increases the N,N- dialkyl(diphenylphosphinomethylene)-iminium yield approximately twice. One of the reaction intermediates is shown to be iododiphenylphosphine. The reaction can be regarded as disproportionation.
SYNTHESIS AND INFRARED STUDY OF (C6H5)nPX3-nCr(CO)5 (X=Cl, Br, I, H; n=0-3) AND (C6H5)2PRCr(CO)5 (R=METHYL, ETHYL, i-PROPYL, t-BUTYL) COMPOUNDS
Vincent, E.,Verdonck, L.,Kelen, G. P. van der
, p. 33 - 40 (2007/10/02)
A method for the preparation of (C6H5)nPX3-nCr(CO)5 complexes in the crystalline state is described.The carbon-oxygen stretching vibration, νCO(A1 eq.), of the complexes with X=Cl, Br, I is mainly determined by the inductive effect of the (C6H5)nPX3-n group.For X=H, the νCO band is defined by the concomitant influence of the ?, ? and steric effects.
NMR STUDY OF (C6H5)3-nPXn (X = Cl, Br, I; n = 0-3) AND (C6H5)3-nPXnCr(CO)5 COMPOUNDS
Vincent, E.,Verdonck, L.,Kelen, G. P. van der
, p. 239 - 248 (2007/10/02)
The 31P chemical shift of the (C6H5)3-nPXn ligands (X = Cl, Br, I; n = 0-3) is dominated by the electronegativity of the substituents. ? bonding is only important for derivatives with three strongly electronegative substituents.The 3
