92594-09-7

Basic information

• Product Name: Furan, tetrahydro-2-methoxy-2-phenyl-
• CAS NO: 92594-09-7
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Mol File: 92594-09-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Furan, tetrahydro-2-methoxy-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Furan, tetrahydro-2-methoxy-2-phenyl-(92594-09-7)
• EPA Substance Registry System: Furan, tetrahydro-2-methoxy-2-phenyl-(92594-09-7)

Safety Data

• Hazardous Substances Data: 92594-09-7(Hazardous Substances Data)

Upstream product

• 939-52-6 4-chloro-1-phenylbutan-1-one 
• 67-56-1 methanol 
• 16133-83-8 tetrahydro-2-phenylfuran 
• 124-41-4 sodium methylate 

Relevant articles and documents

Palladium on Carbon-Catalyzed Benzylic Methoxylation for Synthesis of Mixed Acetals and Orthoesters

The palladium on carbon (Pd/C)-catalyzed direct methoxylation of the benzylic positions of linear benzyl and cyclic ether substrates proceeded in the presence of i-Pr2NEt under an oxygen atmosphere to give the corresponding mixed acetals. Cyclic acetal derivatives could also be converted into orthoesters. The present direct methoxylation via a carbon-hydrogen (C?H) functionalization can be accomplished using the easily-removed Pd/C and molecular oxygen as a green oxidant. The obtained mixed acetals were transformed into the corresponding ether products by chemoselective substitution of the methoxy group using a silyltriflate, 2,4,6-collidine, and a nucleophile. The orthoester derivative could also be transformed into the cyclic ketal under similar reaction conditions.