92664-38-5

Basic information

• Product Name: 1-(4-METHYLPIPERAZIN-1-YL)PROP-2-EN-1-ONE
• Synonyms: 1-(4-METHYLPIPERAZIN-1-YL)PROP-2-EN-1-ONE
• CAS NO: 92664-38-5
• Molecular Formula: C8H14N2O
• Molecular Weight: 0
• Mol File: 92664-38-5.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-METHYLPIPERAZIN-1-YL)PROP-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHYLPIPERAZIN-1-YL)PROP-2-EN-1-ONE(92664-38-5)
• EPA Substance Registry System: 1-(4-METHYLPIPERAZIN-1-YL)PROP-2-EN-1-ONE(92664-38-5)

Safety Data

• Hazardous Substances Data: 92664-38-5(Hazardous Substances Data)

Upstream product

• 109-01-3 1-methyl-piperazine 
• 79-10-7 acrylic acid 
• 814-68-6 acryloyl chloride 

Relevant articles and documents

Method for catalytically synthesizing acrylamide compound by MOFs-derived zirconium-based ternary oxide solid acid

The invention provides a catalytic synthesis of acrylamide compounds with zirconium-based ternary oxide solid acid as a catalyst, and the low-temperature activity is good. In the synthesis process, the acid is small, the reaction conditions are mild and controllable, the byproducts are few, the reaction yield is effectively improved, the purity is high, the quality is good, and the method is suitable for large-scale production.

COVALENT TARGETING OF E3 LIGASES

Disclosed herein, inter alia, are compositions and methods for targeting E3 ligases. In an aspect is a targeted protein degrader including 1) a targeted protein binder and 2) an E3 Ubiquitin ligase binder, wherein the E3 Ubiquitin ligase is human RNF4 or human RNF114. In an aspect is provided a pharmaceutical composition including a compound as described herein, including embodiments, and a pharmaceutically acceptable excipient.

Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

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