92668-56-9Relevant academic research and scientific papers
N1- and N3-Arylations of Hydantoins Employing Diaryliodonium Salts via Copper(I) Catalysis at Room Temperature
Abha Saikia, Raktim,Barman, Dhiraj,Dutta, Anurag,Jyoti Thakur, Ashim
, p. 400 - 410 (2020/12/17)
Copper(I)-catalyzed N-arylation (both N1- and N3-) of hydantoins with diaryliodonium salts as aryl partners at room temperature is reported. The transformation allows diverse scopes on both hydantoins and diaryliodonium salts deliver
Comparison of copper(II) acetate promoted N-arylation of 5,5-dimethyl hydantoin and other imides with triarylbismuthanes and aryl boronic acids
Hügel, Helmut M.,Rix, Colin J.,Fleck, Karin
, p. 2290 - 2292 (2007/10/03)
This work demonstrates that the copper acetate promoted N-arylation of imides with boronic acids can be employed as a major method for the synthesis of N3-aryl hydantoins. Georg Thieme Verlag Stuttgart.
3-Arylhydantoine, a class of schistosomicidal compounds
Link,Stohler
, p. 261 - 265 (2007/10/02)
A series of derivatives of 3-arylhydantoin was synthesized and submitted to a broad pharmacological screening. Unexpectedly, some of the tested compounds showed interesting activity against infection with Schistosoma mansoni. From a study on structure-act
