926893-06-3Relevant academic research and scientific papers
Structure-activity relationships of aryloxyalkanoic acid hydroxyamides as potent inhibitors of histone deacetylase
Marson, Charles M.,Mahadevan, Thevaki,Dines, Jon,Sengmany, Stephane,Morrell, James M.,Alao, John P.,Joel, Simon P.,Vigushin, David M.,Charles Coombes
, p. 136 - 141 (2007/10/03)
Syntheses of aryloxyalkanoic acid hydroxyamides are described, all of which are potent inhibitors of histone deacetylase, some being more potent in vitro than trichostatin A (IC50 = 3 nM). Variation of the substituents on the benzene ring as we
