92740-48-2 Usage
General Description
(2-Naphthylsulfonyl)amino]acetic acid is a chemical compound containing a naphthalene ring and an amino acid group. It is commonly used as a building block in the synthesis of various organic compounds and pharmaceuticals. (2-NAPHTHYLSULFONYL)AMINO]ACETIC ACID has been found to possess antibacterial and anti-tubercular properties, and has been used as a potential drug candidate in the treatment of bacterial and mycobacterial infections. Additionally, it has been studied for its potential as an anti-inflammatory agent due to its ability to inhibit the production of pro-inflammatory molecules. Overall, (2-Naphthylsulfonyl)amino]acetic acid is a versatile compound with potential applications in medicinal chemistry and pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 92740-48-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,7,4 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 92740-48:
(7*9)+(6*2)+(5*7)+(4*4)+(3*0)+(2*4)+(1*8)=142
142 % 10 = 2
So 92740-48-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO4S/c14-12(15)8-13-18(16,17)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,13H,8H2,(H,14,15)/p-1
92740-48-2Relevant articles and documents
Serine protease inhibitors
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, (2008/06/13)
PCT No. PCT/GB96/00352 Sec. 371 Date Mar. 30, 1998 Sec. 102(e) Date Mar. 30, 1998 PCT Filed Feb. 15, 1996 PCT Pub. No. WO96/25427 PCT Pub. Date Aug. 22, 1996This invention is directed to peptide inhibitors of serine proteases, espcecially thrombin, in which the P1-P2 natural amide linkage is replaced by another bond. Exemplary thrombin inhibitors have the formula: X-(aa3)-(aa2)- psi -(aa1)-Z wherein X is H or a substituent on the N-terminal amino group, aa3 is a hydrophobic amino acid, aa23 is Pro, aa1 is Arg or an Arg analgoue, Z is -COOH or a heteroatom acid group and psi is a non-amide linkage.
Design and synthesis of potent and highly selective thrombin inhibitors
Hilpert,Ackermann,Banner,Gast,Gubernator,Hadvary,Labler,Muller,Schmid,Tschopp,Van de Waterbeemd
, p. 3889 - 3901 (2007/10/02)
Thrombin, a serine protease, plays a central role in the initiation and propagation of thrombotic events. An extensive search for new thrombin inhibitors was performed, using an unconventional approach. Screening of small basic molecules for binding in th
In vitro aldose reductase inhibitory activity of substituted N-benzenesulfonylglycine derivatives
DeRuiter,Brubaker,Garner,Barksdale,Mayfield
, p. 149 - 152 (2007/10/02)
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