92757-70-5

Basic information

• Product Name: 1-Butanone, 1-[5-acetyl-2-(benzoyloxy)phenyl]-
• CAS NO: 92757-70-5
• Molecular Formula: C19H18O4
• Molecular Weight: 310.35
• Mol File: 92757-70-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-[5-acetyl-2-(benzoyloxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-[5-acetyl-2-(benzoyloxy)phenyl]-(92757-70-5)
• EPA Substance Registry System: 1-Butanone, 1-[5-acetyl-2-(benzoyloxy)phenyl]-(92757-70-5)

Safety Data

• Hazardous Substances Data: 92757-70-5(Hazardous Substances Data)

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 75305-82-7 4-acetylphenyl butyrate 
• 98-88-4 benzoyl chloride 
• 92757-66-9 1-(5-Acetyl-2-hydroxy-phenyl)-butan-1-one 

Downstream Products

• 92757-66-9 1-(5-Acetyl-2-hydroxy-phenyl)-butan-1-one 
• 92757-74-9 6-Acetyl-3-ethyl-2-phenyl-chromen-4-one 
• 65-85-0 benzoic acid 

Relevant articles and documents

Synthesis of 6-Acetyl-3-alkyl-2-phenyl-chromen-4-ones by Phasetransfer Catalysed Baker-Venkataraman Reaction

Three of the five partial steps of the Baker-Venkataramansynthesis of flavones (scheme 1) can be flavoured by PTC conditions.In the intermolecular O-acylations of the 4-hydroxyacetophenone 1 (A) and the 5-acetyl-2-hydroxy-acylophenones 3 (C), respectively, the nucleophilicity of the phenolat anions is increased by the PT catalysator.The steric and electronic effects of the substituents in the 5-acetyl-2-benzoyloxy-acylophenones 4 cause the formation of the 6-acetyl-flavones 6 in the phasetransfer catalysed Baker-Venkataraman rearrangement (D) in one step and in good yields.The over-all yields of the 1 -> 6 reactions are not higher than 30percent because of the limiting step (B).This Fries rearrangement of 4-acyloxy-acetophenones 2 affords only 32-62percent of 3 under drastically enhanced conditions.