927898-77-9

Upstream product

• 927898-75-7 4-oxo-5-phenylpentanoic anhydride 
• 100-46-9 benzylamine 
• 69063-22-5 (Z)-γ-benzylidene-γ-butyrolactone 
• 2142-06-5 1-(phenylmethyl)-2,5-pyrrolidinedione 
• 6921-34-2 benzylmagnesium chloride 
• 64984-60-7 4-oxo-4-[(phenylmethyl)amino]butanoic acid 
• 100-44-7 benzyl chloride 
• 3183-15-1 4-oxo-5-phenylvaleric acid 

Downstream Products

• 1447820-02-1 1-benzyl-5-benzyl-5-[2-(methyloxycarbonyl)ethyl]pyrrolidin-2-one 
• 1447820-03-2 1-benzyl-5-benzyl-5-[2-(tert-butyloxycarbonyl)ethyl]pyrrolidin-2-one 
• 1447820-04-3 1-benzyl-5-benzyl-5-(2-cyanoethyl)pyrrolidin-2-one 
• 127419-78-7 1,5-bis(phenylmethyl)-2-pyrrolidinone 

Relevant academic research and scientific papers

Palladium-catalyzed C - O hydrogenolysis in γ-hydroxy γ-lactams as an efficient approach to 5-alkyl(aryl)pyrrolidin-2-ones

5-R-Pyrrolidin-2-ones were synthesized by Pd/Sibunit-catalyzed C - O hydrogenolysis of 5-R-5-hydroxypyrrolidin-2-ones with molecular hydrogen.

Umpolung of hemiaminals: Titanocene-catalyzed dehydroxylative radical coupling reactions with activated alkenes

Radical measures: A radical coupling reaction, which is proposed to proceed through in situ chlorination of a hydroxy group by Me3SiCl, is used to form quaternary carbon centers with amino groups in α position. The reaction can be scaled up and

A tereoselective synthesis of 2-benzylidenepyrrolidin-5-ones from the amides of 4-oxo-5-phenylpentanoic acid or their tautomers, (2-benzyl-2- hydroxypyrrolidin-5-ones)

The reactions of primary amines with the anhydride 6 or the lactone 7 (γ-benzylidene-γ-butyrolactone) of 4-oxo-5-phenylpentanoic acid, gave depending on reaction conditions either: (a) the γ-keto amides 8 or their cyclic tautomers 9 (2-benzyl-2-hydroxypyr