928149-85-3 Usage
Derivative of indole
Indole is a heterocyclic aromatic organic compound The compound is based on the indole structure, which is a five-membered aromatic ring with a nitrogen atom.
Thioamide functional group
A sulfur analog of an amide The compound contains a thioamide group, which is similar to an amide group but with a sulfur atom replacing the oxygen atom.
Chlorine atom
Unique properties and potential applications The presence of a chlorine atom in the structure contributes to the compound's unique properties and may lead to various applications in organic synthesis and drug discovery.
Cyclohexylmethyl group
Influences the compound's properties and applications The inclusion of a cyclohexylmethyl group affects the compound's structure and properties, further expanding its potential uses in scientific and industrial fields.
Interest to researchers
Various scientific and industrial fields Due to its structure and chemical properties, 1H-Indole-3-carbothioamide, 7-chloro-1-(cyclohexylmethyl)is of interest to researchers working in organic synthesis, drug discovery, and other related areas.
Check Digit Verification of cas no
The CAS Registry Mumber 928149-85-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,1,4 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 928149-85:
(8*9)+(7*2)+(6*8)+(5*1)+(4*4)+(3*9)+(2*8)+(1*5)=203
203 % 10 = 3
So 928149-85-3 is a valid CAS Registry Number.
928149-85-3Relevant academic research and scientific papers
Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate
Ratcliffe, Paul,Adam, Julia M.,Baker, James,Bursi, Roberta,Campbell, Robert,Clark, John K.,Cottney, Jean E.,Deehan, Maureen,Easson, Anna-Marie,Ecker, Daniel,Edwards, Darren,Epemolu, Ola,Evans, Louise,Fields, Ruth,Francis, Stuart,Harradine, Paul,Jeremiah, Fiona,Kiyoi, Takao,McArthur, Duncan,Morrison, Angus,Passier, Paul,Pick, Jack,Schnabel, Peter G.,Schulz, Jurgen,Steinbrede, Heinz,Walker, Glenn,Westwood, Paul,Wishart, Grant,Haes, Joanna Udo De
, p. 2541 - 2546 (2011/06/17)
We report an expansion of the structure-activity relationship (SAR) of a novel series of indole-3-heterocyclic CB1 receptor agonists. Starting from the potent but poorly soluble lead, 1, a rational approach was taken in order to balance solubility, hERG a
