928149-84-2 Usage
Molecular Structure
1H-Indole, 7-chloro-3-[4-(chloromethyl)-2-thiazolyl]-1-(cyclohexylmethyl)is a complex organic compound consisting of an indole ring with various functional groups attached to it.
Indole Ring
The core structure of the compound is an indole ring, which is a bicyclic aromatic system with a ten-membered ring containing a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring.
Chlorine Substitution
The indole ring has a chlorine atom substituted at the 7th position, which imparts additional reactivity and properties to the molecule.
Thiazole Ring
One of the functional groups present in the compound is a thiazole ring, which is a five-membered heterocyclic ring containing one sulfur and one nitrogen atom.
Chloromethyl Group
Attached to the thiazole ring is a chloromethyl group (-CH2Cl), which is a methyl group with a chlorine atom attached to the hydrogen, enhancing the compound's reactivity and potential applications.
Cyclohexylmethyl Group
Another functional group present in the compound is a cyclohexylmethyl group (-CH2-C6H11), which is a methyl group attached to a cyclohexane ring, adding steric bulk and lipophilicity to the molecule.
Potential Applications
Due to its diverse chemical structure, 1H-Indole, 7-chloro-3-[4-(chloromethyl)-2-thiazolyl]-1-(cyclohexylmethyl)has potential uses in pharmaceuticals and agrochemicals, as it may exhibit a wide range of biological activities.
Biological Activities
The presence of various functional groups in the compound may allow it to interact with different biological targets, such as enzymes, receptors, or ion channels, leading to potential therapeutic or pesticidal effects.
Check Digit Verification of cas no
The CAS Registry Mumber 928149-84-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,1,4 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 928149-84:
(8*9)+(7*2)+(6*8)+(5*1)+(4*4)+(3*9)+(2*8)+(1*4)=202
202 % 10 = 2
So 928149-84-2 is a valid CAS Registry Number.
928149-84-2Relevant academic research and scientific papers
Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate
Ratcliffe, Paul,Adam, Julia M.,Baker, James,Bursi, Roberta,Campbell, Robert,Clark, John K.,Cottney, Jean E.,Deehan, Maureen,Easson, Anna-Marie,Ecker, Daniel,Edwards, Darren,Epemolu, Ola,Evans, Louise,Fields, Ruth,Francis, Stuart,Harradine, Paul,Jeremiah, Fiona,Kiyoi, Takao,McArthur, Duncan,Morrison, Angus,Passier, Paul,Pick, Jack,Schnabel, Peter G.,Schulz, Jurgen,Steinbrede, Heinz,Walker, Glenn,Westwood, Paul,Wishart, Grant,Haes, Joanna Udo De
, p. 2541 - 2546 (2011/06/17)
We report an expansion of the structure-activity relationship (SAR) of a novel series of indole-3-heterocyclic CB1 receptor agonists. Starting from the potent but poorly soluble lead, 1, a rational approach was taken in order to balance solubility, hERG a
(INDOL-3-YL)-HETEROCYCLE DERIVATIVES AS AGONISTS OF THE CANNABINOID CB1 RECEPTOR
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Page/Page column 31-32, (2010/11/26)
The invention relates to indole derivative having the general Formula (I) Wherein A, X1, X2, X3, Y, R1, R2, R3 and R4 are as defined in the claims, or a pharmaceutically acceptab
Indole derivatives
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Page/Page column 15, (2010/11/26)
Disclosed herein are indole derivatives of the formula (I) wherein each of the substitutents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing the indole derivatives and use of
