928406-68-2

Upstream product

• 6027-21-0 D-homoserine 
• 1161-13-3 N-Cbz-L-Phe 

Downstream Products

• 5241-56-5 benzyl [(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate 
• 928406-70-6 {(S)-1-[(R)-3-(tert-Butyl-diphenyl-silanyloxy)-1-carbamoyl-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 
• 928406-71-7 {(S)-1-[(R)-1-Amino-3-(tert-butyl-diphenyl-silanyloxy)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 
• 928406-63-7 ((S)-1-{(2R,4S)-2-[Bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylcarbamoyl}-2-phenyl-ethyl)-carbamic acid benzyl ester 
• 928406-62-6 ((S)-1-{(2S,4S)-2-[Bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylcarbamoyl}-2-phenyl-ethyl)-carbamic acid benzyl ester 
• 928406-72-8 [(S)-1-((R)-1-Amino-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester 
• 928406-69-3 [(S)-1-((R)-1-Carbamoyl-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Phenylalanyl-aminocyclophosphamides as model prodrugs for proteolytic activation: Synthesis, stability, and stereochemical requirements for enzymatic cleavage

4-Aminocyclophosphamide (4-NH2-CPA, 7) was proposed as a prodrug moiety of phosphoramide mustard. Four diastereomers of phenylalanine-conjugates of 4-NH2-CPA were synthesized and their stereochemistry was assigned based on chromatogr