92856-34-3

Basic information

• Product Name: N-(2,5-DIOXO-5,6,7,8-TETRAHYDRO-2H-CHROMEN-3-YL)BENZENECARBOXAMIDE
• Synonyms: N-(2,5-DIOXO-5,6,7,8-TETRAHYDRO-2H-CHROMEN-3-YL)BENZENECARBOXAMIDE;N-(2,5-dioxo-5,6,7,8-tetrahydro-2H-chromen-3-yl)benzamide
• CAS NO: 92856-34-3
• Molecular Formula: C₁₆H₁₃NO₄
• Molecular Weight: 283.28
• Mol File: 92856-34-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2,5-DIOXO-5,6,7,8-TETRAHYDRO-2H-CHROMEN-3-YL)BENZENECARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,5-DIOXO-5,6,7,8-TETRAHYDRO-2H-CHROMEN-3-YL)BENZENECARBOXAMIDE(92856-34-3)
• EPA Substance Registry System: N-(2,5-DIOXO-5,6,7,8-TETRAHYDRO-2H-CHROMEN-3-YL)BENZENECARBOXAMIDE(92856-34-3)

Safety Data

• Hazardous Substances Data: 92856-34-3(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 504-02-9 1,3-cylohexanedione 
• 149-73-5 trimethyl orthoformate 
• 122-51-0 orthoformic acid triethyl ester 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 56952-04-6 methyl 2-N-benzoylamino-3-N,N-dimethylamino-2-propenoate 
• 60777-96-0 (Z)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one 
• 14036-06-7 diethoxymethyl acetate 
• 15646-46-5 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one 
• 85302-07-4 2-(dimethylaminomethylene)cyclohexane-1,3-dione 
• 107872-68-4 2-benzoylamino-3-chloro-acrylic acid 

Downstream Products

• 1611491-68-9 N-(5-hydroxy-2-oxo-2H-chromen-3-yl)benzamide 
• 163465-76-7 N-(5,6,7,8-tetrahydro-8-oxonaphthalen-2-yl)benzamide 
• 161038-38-6 methyl 3-(benzoylamino)-5,6,7,8-tetrahydro-2,5-dioxo-1(2H)-quinolineacetate 
• 161038-39-7 N-<1-(carbazoylmethyl)-1,2,5,6,7,8-hexahydro-5-hydrazono-2-oxo-3-quinolinyl>benzamide 

Relevant articles and documents

Intermediate products, methods for their preparation and use thereof

Novel solid supported intermediate products of the general formula coupled to a solid polymeric support through one or both of the R1 groups or through the R4 group which are suitable for synthesis of heterocyclic compounds are disclosed. Methods for preparing such intermediate products are also disclosed and also the use of the intermediate products in simple and fast methods on solid phase for synthesis of heterocycles.

Ethyl or methyl 6-substituted 3-(benzoylamino)-2-oxo-2H-pyran-5- carboxylates and 3-(benzoylamino)-7,8-dihydro-2H-1-benzopyran-2,5(6H)-diones with local anesthetic, platelet antiaggregating and other activities

The synthesis of ethyl or methyl 6-substituted 3-(benzoylamino)-2-oxo-2H- pyran-5-carboxylates 2 and 3-(benzoylamino)-7,8-dihydro-2H-1-benzopyran- 2,5(6H)-diones 4 by reaction of hippuric acid in acetic anhydride with ethyl or methyl 2-dimethylaminomethylene-3-oxoalkanoates and 2- dimethylaminomethylene-1,3-cyclohexanediones, respectively, is described. Some compounds 2 and 4 showed a strong local anesthetic activity in mice and a platelet antiaggregating activity in vitro comparable to that of acetylsalicylic acid, as well as moderate analgesic, antiinflammatory and antiarrhythmic activities in rats and mice.

A simple and general one-pot synthesis of some 2h-pyran-2-ones and fused pyran-2-ones

A general one-pot synthesis of some 2H-pyran-2-ones and fused pyran-2-ones starting from 1,3-dlcarbonyl compounds, N-acylglycines and one-carbon synthons (trialkyl orthoformates, diethoxymethyl acetate or N,N-dlmethylformamide dimethyl acetal) in acetic anhydride (or in a mixture of acetic anhydride and acetic acid) is described.