928653-73-0 Usage
Uses
Used in Organic Synthesis:
5-Bromo-2-chloro-3-iodo-pyridine is used as a versatile building block for the synthesis of more complex organic compounds. Its unique combination of halogen atoms allows for a wide range of chemical reactions and transformations, making it a valuable intermediate in the preparation of various organic molecules.
Used in Chemical Reactions:
5-Bromo-2-chloro-3-iodo-pyridine is used as a reagent in different chemical reactions. Its high reactivity and the presence of multiple halogens enable it to participate in various reaction pathways, such as substitution, elimination, and coupling reactions, contributing to the formation of new compounds with desired properties.
Used in Pharmaceutical Industry:
5-Bromo-2-chloro-3-iodo-pyridine is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structural features and reactivity make it suitable for the development of new drugs with potential therapeutic applications.
Used in Material Science:
5-Bromo-2-chloro-3-iodo-pyridine is used in the development of new materials with specific properties. Its reactivity and the presence of multiple halogens allow for the creation of novel materials with tailored characteristics, such as improved stability, enhanced reactivity, or specific optical, electronic, or magnetic properties.
Used in Research and Development:
5-Bromo-2-chloro-3-iodo-pyridine is used as a research compound in academic and industrial laboratories. Its unique properties and reactivity make it an interesting subject for studying various aspects of chemistry, such as reaction mechanisms, structure-property relationships, and the development of new synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 928653-73-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,6,5 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 928653-73:
(8*9)+(7*2)+(6*8)+(5*6)+(4*5)+(3*3)+(2*7)+(1*3)=210
210 % 10 = 0
So 928653-73-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H2BrClIN/c6-3-1-4(8)5(7)9-2-3/h1-2H
928653-73-0Relevant articles and documents
BCL-2 FAMILY PROTEINS MODULATING COMPOUNDS FOR CANCER TREATMENT
-
Paragraph 55; 57; 58, (2021/09/17)
The present invention relates to compounds, compositions and methods for treating cancers and disorders of cell proliferation and more particularly, methods of making and using compounds that modulate at least one of the proteins chosen from Bcl-2, Mcl-1,
Br vs. TsO Chemoselective Suzuki–Miyaura Cross-Coupling Reaction on Nicotinaldehyde Moiety for the Preparation of 2,3,5-Trisubstituted Pyridines
Hédou, Damien,Voisin-Chiret, Anne Sophie
supporting information, p. 3640 - 3649 (2020/06/10)
Br vs. TsO chemoselective pallado-catalyzed Suzuki–Miyaura reaction has been developed from the 5-bromo-2-tosyloxynicotinaldehyde for the preparation of polysubstituted pyridines. This methodology has been applied for the preparation of a terpyridine alde
First evidence that oligopyridines, α-helix foldamers, inhibit Mcl-1 and sensitize ovarian carcinoma cells to Bcl-xL-targeting strategies
Gloaguen, Céline,Voisin-Chiret, Anne Sophie,Sopkova-De Oliveira Santos, Jana,Fogha, Jade,Gautier, Fabien,De Giorgi, Marcella,Burzicki, Grégory,Perato, Serge,Pétigny-Lechartier, Cécile,Simonin-Le Jeune, Karin,Brotin, Emilie,Goux, Didier,N'Diaye, Monique,Lambert, Bernard,Louis, Marie-Hélène,Ligat, Laetitia,Lopez, Frédéric,Juin, Philippe,Bureau, Ronan,Rault, Sylvain,Poulain, Laurent
, p. 1644 - 1668 (2015/03/18)
Apoptosis control defects such as the deregulation of Bcl-2 family member expression are frequently involved in chemoresistance. In ovarian carcinoma, we previously demonstrated that Bcl-xL and Mcl-1 cooperate to protect cancer cells against ap
MCL-1 MODULATING COMPOUNDS FOR CANCER TREATMENT
-
Page/Page column 22; 23; 28, (2015/09/28)
The invention relates to compounds of formula (I), and to their therapeutic use in the treatment of cancer : Wherein Y1, Y2, Ar1, Ar2, R1, R2, i, j, k, 1 are as defined in claim 1