928768-36-9Relevant academic research and scientific papers
Rhodium-Catalyzed Domino Hydroformylation/Double-Cyclization Reaction of Arylacetylenecarboxamides: Diastereoselectivity Studies and Application in the Synthesis of 1-Azabicyclo[x.y.0]alkanes
Tsai, Jui-Chi,Lin, Yi-Huei,Chen, Guei-Tang,Gao, Yu-Kai,Tseng, Yu-Che,Kao, Chien-Lun,Chiou, Wen-Hua
supporting information, p. 3190 - 3197 (2018/10/25)
A domino method for the rapid syntheses of 1-azabicyclo[x.y.0]alkane scaffolds, such as indolizidines, quinolizidines, decahydropyridoazepines, and their derivatives, has been developed. This strategy involved a rhodium-catalyzed hydroformylation of allyl
The combination of relay and cooperative catalysis with a gold/palladium/brnsted acid ternary system for the cascade hydroamination/ allylic alkylation reaction
Wu, Hua,He, Yu-Ping,Gong, Liu-Zhu
, p. 975 - 980 (2012/05/20)
The combination of relay and cooperative catalysis with a gold/palladium/Brnsted acid ternary system renders a cascade hydroamination/allylic alkylation reaction to provide an unprecedented entry to pyrrolidine derivatives in high yields. Copyright
Application of the intramolecular PIFA-mediated amidation of alkynes to the synthesis of substituted indolizidinones
Pardo, Leticia M.,Tellitu, Imanol,Domínguez, Esther
, p. 3692 - 3700 (2012/06/30)
The construction of the title compounds has been achieved from properly substituted linear alkynylamides through the suitable combination of two key cyclization steps. First, an intramolecular PIFA-mediated alkyne amidation protocol leads to the creation
Alkyne-mediated domino hydroformylation/double cyclization: Mechanistic insight and synthesis of (±)-tashiromine
Chiou, Wen-Hua,Lin, Yi-Huei,Chen, Guei-Tang,Gao, Yu-Kai,Tseng, Yu-Che,Kao, Chien-Lun,Tsai, Jui-Chi
, p. 3562 - 3564 (2011/04/26)
A novel domino reaction, alkyne-mediated domino hydroformylation/double cyclization, has been developed for rapid preparation of indolizidine type alkaloids. DFT calculations were applied for rationales of reactivity and selectivity. A concise synthesis of tashiromine as the application of the methodology is also reported.
Intramolecular PIFA-mediated alkyne amidation and carboxylation reaction
Tellitu, Imanol,Serna, Sonia,Herrero, M. Teresa,Moreno, Isabel,Dominguez, Esther,SanMartin, Raul
, p. 1526 - 1529 (2007/10/03)
(Chemical Equation Presented) The hypervalent iodine reagent PIFA promotes the intramolecular electrophilic cyclization of easily accessible alkynylamides and alkynyl carboxylic acids, leading to the formation of pyrrolidinone and lactone skeletons, respe
