928853-75-2Relevant academic research and scientific papers
Design and synthesis of pyrimido[4,5-b][1,4]benzothiazine derivatives, as potent 15-lipoxygenase inhibitors
Bakavoli,Nikpour,Rahimizadeh,Saberi,Sadeghian
, p. 2120 - 2126 (2008/02/04)
A group of 2-substituted pyrimido[4,5-b][1,4]benzothiazines were designed, synthesized, and evaluated as potential inhibitors of 15-lipoxygenase (15-LO). Compounds 4d and 4e showed the best IC50 of 15-LO inhibition (IC50 = 18 and 34
