929040-77-7Relevant academic research and scientific papers
Synthesis and anti-influenza a virus activity of 6′-amino-6′-deoxy-glucoglycerolipids analogs
Ren, Li,Zhang, Jun,Ma, Haizhen,Sun, Linlin,Zhang, Xiaoshuang,Yu, Guangli,Guan, Huashi,Wang, Wei,Li, Chunxia
, (2016/07/06)
A series of aminoglucoglycerolipids derivatives had been synthesized, including 6′-acylamido-glucoglycerolipids 1a-1f and corresponding 2′-acylamido-glucoglycerolipids 2a-2c bearing different fatty acids, glucosyl diglycerides 3a-3e bearing different func
NOVEL SYNTHETIC OLIGOMERS OF NEISSERIA MENINGITIS SEROGROUP X AND PROCESS OF PREPARING THEM
-
, (2015/09/28)
The present invention relates to synthesis of novel higher oligomers and process of preparing the same. In particular the present invention relates to the chemical synthesis of oligomers of Neisseria meningitidis serogroup X ('hereinafter Men-X), more par
Synthesis of the heparin-based anticoagulant drug fondaparinux
Chang, Cheng-Hsiu,Lico, Larry S.,Huang, Teng-Yi,Lin, Shu-Yi,Chang, Chi-Liang,Hung, Shang-Cheng,Arco, Susan D.
, p. 9876 - 9879,4 (2014/10/15)
Fondaparinux, a synthetic pentasaccharide based on the heparin antithrombin-binding domain, is an approved clinical anticoagulant. Although it is a better and safer alternative to pharmaceutical heparins in many cases, its high cost, which results from th
Study of the stereoselectivity of 2-azido-2-deoxyglucosyl donors: Protecting group effects
Ngoje, George,Li, Zhitao
, p. 1879 - 1886 (2013/04/23)
A series of tolyl 2-azido-2-deoxy-thio-glucoside donors with different combinations of protecting groups were prepared. These donors were used in glycosylation reactions to test the correlations between the stereoselectivity and the pattern of the protect
Application of 2-azido-2-deoxythioglycosides for β-glycoside formation and oligosaccharide synthesis
Mong, Kwok-Kong Tony,Yen, Yu-Fang,Hung, Wei-Cheng,Lai, Yen-Hsun,Chen, Jiun-Han
, p. 3009 - 3017 (2012/06/30)
Most natural 2-acetamido-2-deoxyglycosides exist in a 1,2-trans-β- glycosidic configuration. This study investigated the use of 2-azido-2-deoxythioglycosides for 1,2-trans-β-glycosidic bond formation under low-concentration glycosylation conditions. Furth
Rate-dependent inverse-addition β-selective mannosylation and contiguous sequential glycosylation involving β-mannosidic bond formation
Chang, Shih-Sheng,Shih, Che-Hao,Lai, Kwun-Cheng,Mong, Kwok-Kong Tony
, p. 1152 - 1162 (2011/07/07)
The β-selectivity of mannosy-lation has been found to be dependent on the addition rate of the mannosyl trichloroacetimidate donor in an inverse-addition (I-A) procedure. This rate dependent I-A procedure can improve the selectivity of direct β-mannosylat
Highly efficient syntheses of hyaluronic acid oligosaccharides
Huang, Lijun,Huang, Xuefei
, p. 529 - 540 (2007/10/03)
Highly efficient syntheses of hyaluronic acid oligosaccharides have been accomplished through the pre-activation based iterative one-pot strategy. A series of oligosaccharides ranging from di- to hexasaccharides were rapidly assembled using only near stoi
