501088-37-5

Upstream product

• 929040-77-7 4-methylphenyl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-1-thio-α,β-D-glucopyranoside 
• 171032-74-9 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose 
• 220645-20-5 p-methylphenyl 3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranoside 

Downstream Products

• 501088-45-5 p-methylphenyl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-thio-β-D-glucopyranoside 
• 1235137-50-4 p-tolyl 2-deoxy-2-azido-3-O-benzyl-4,6-O-benzylidene-1-thio-α-D-glucopyranoside 
• 502692-41-3 p-tolyl 2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-1-thio-β-D-glucopyranoside 
• 1461641-29-1 methyl 2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-glucopyranosyl-(1→4)-2,3-di-O-benzyl-1-O-methyl-α-D-glucopyranosyluronate 
• 1461641-30-4 methyl 2-azido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl-(1→4)-2,3-di-O-benzyl-1-O-methyl-α-D-glucopyranosyluronate 
• 1262201-90-0 p-tolyl 6-O-acetyl-2-azido-2-deoxy-thio-1-β-D-glucopyranoside 
• 1053181-27-3 C₁₆H₂₁N₃O₄S 
• 502692-45-7 Acetic acid (2S,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(2R,3S,4R,5R,6S)-4-benzyloxy-2-benzyloxymethyl-6-p-tolylsulfanyl-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-3-yl ester 
• 502692-44-6 p-tolyl 3,6-di-O-benzyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxy)carbamoylamino-β-D-glucopyranoside 
• 502692-43-5 (2R,3S,4R,5R,6S)-5-Amino-4-benzyloxy-2-benzyloxymethyl-6-p-tolylsulfanyl-tetrahydro-pyran-3-ol 
• 502692-42-4 p-tolyl 2-azido-3,6-di-O-benzyl-2-deoxy-1-thio-β-D-glucopyranoside 
• 501088-50-2 (2R,4aR,6S,7R,8R,8aS)-7-Azido-2-phenyl-6-p-tolylsulfanyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 

Relevant academic research and scientific papers

Synthesis of the heparin-based anticoagulant drug fondaparinux

Fondaparinux, a synthetic pentasaccharide based on the heparin antithrombin-binding domain, is an approved clinical anticoagulant. Although it is a better and safer alternative to pharmaceutical heparins in many cases, its high cost, which results from th

Low-concentration 12-trans β-selective glycosylation strategy and its applications in oligosaccharide synthesis

This study develops an operationally easy, efficient, and general 1,2-trans β-selective glycosylation reaction that proceeds in the absence of a C2 acyl function. This process employs chemically stable thioglycosyl donors and low substrate concentrations to achieve excellent β-selectivities in glycosylation reactions. This method is widely applicable to a range of glycosyl substrates irrespective of their structures and hydroxyl-protecting functions. This low-concentration 1,2-trans β-selective glycosylation in carbohydrate chemistry removes the restriction of using highly reactive thioglycosides to construct 1,2-trans β-glycosidic bonds. This is beneficial to the design of new strategies for oligosaccharide synthesis, as illustrated in the preparation of the biologically relevant β-(1-6)-glucan trisaccharide, β-linked Gb3 and isoGb3 derivatives.

A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers

Poly-N-acetyllactosamine oligomer is a type-2 glycan core from which a number of important bioactive glycoconjugates are assembled in vivo. Development of an effective synthesis of N-acetyllactosamine oligomers will therefore provide a new chemoenzymatic