929075-62-7

Upstream product

• 913955-36-9 (4-chloro-phenyl)[3-methyl-2-(trifluoromethyl)-1H-indol-1-yl]-methanone 
• 154875-87-3 N-(2-ethylphenyl)-2,2,2-trifluoroacetimidoyl chloride 
• 578-54-1 ortho-ethylaniline 
• 913955-35-8 3-methyl-2-(trifluoromethyl)-1H-indole 
• 913962-14-8 N-[2-(1-bromoethyl)phenyl]-2,2,2-trifluoroacetimidoyl chloride 

Downstream Products

• 934843-29-5 dimethyl-2-{[1-(4-chlorobenzoyl)-2-(trifluoromethyl)indol-3-yl]methyl}malonate 
• 132502-93-3 2-trifluoromethyl-indole-3-acetic acid 

Relevant academic research and scientific papers

Grignard cyclization reaction of fluorinated N-arylimidoyl chlorides: A novel and facile access to 2-fluoroalkyl indoles

2-Fluoroalkyl-substituted indole derivatives were simply prepared via the Grignard cyclization reaction (GCR) of corresponding fluorinated N-aryl imidoyl chlorides in good yields. This approach provides a novel and facile access to the biologically import

Fluorinated N-[2-(haloalkyl)phenyl]imidoyl chloride, a key intermediate for the synthesis of 2-fluoroalkyl substituted indole derivatives via Grignard cyclization process

Fluorinated N-[2-(haloalkyl)phenyl]imidoyl chloride, which was readily available from the corresponding anilines by using Uneyama's one-pot synthesis of fluorinated imidoyl chloride, was found to be a key intermediate for the facile synthesis of 2-fluoroa