92945-56-7Relevant academic research and scientific papers
Synthese und Kristallstruktur der Hydroxy-lactone von 6-Methyl-2-propionyl- und 3-Methyl-2-propionylbenzoesaeure
Rudinger-Adler, von Edith,Hostettmann, Maryse,Gramlich, Volker,Petter, Walter
, p. 743 - 747 (1984)
The isomers 6-methyl-2-propionyl- and 3-methyl-2-propionylbenzoic acid were synthesized and separated by DCC (droplet counter-current) chromatography.The crystal structure analyses showed that these compounds are hydroxylactones in the solid state.
Rhodium-catalyzed ortho acylation of aromatic carboxylic acids
Mamone, Patrizia,Danoun, Gregory,Goossen, Lukas J.
supporting information, p. 6704 - 6708 (2013/07/26)
New directions: The carboxylic acid functional group directs the ortho acylation of benzoic acids with carboxylic anhydrides in the presence of a rhodium catalyst (see scheme; cod=cyclo-1,5-octadiene). The acylation at the ortho position is complementary to the meta selectivity of Friedel-Crafts reactions. The resulting products can undergo protodecarboxylation to deliver an aryl ketone. Copyright
