929554-15-4Relevant academic research and scientific papers
Total synthesis of stemaphylline N-oxide and related c9a-epimeric analogues
Schulte, Michael L.,Turlington, Mark L.,Phatak, Sharangdhar S.,Harp, Joel M.,Stauffer, Shaun R.,Lindsley, Craig W.
, p. 11847 - 11852 (2013)
Winning the relay: The first total synthesis of stemaphylline N-oxide has been completed utilizing a bistandem relay ring-closing-metathesis (RRCM) strategy, necessitated by the conformation of the requisite tetraene. This effort also gave unnatural 9a-ep
Stereoselective total synthesis of achaetolide and reconfirmation of its absolute configuration
Srihari,Kumaraswamy,Shankar,Ravishashidhar,Yadav
scheme or table, p. 6174 - 6176 (2011/01/04)
The stereoselective total synthesis of achaetolide 1 has been achieved and its absolute stereochemistry has been reconfirmed to be 3S,6R,7S,9R configuration. Keck allylation, Sharpless asymmetric dihydroxylation, and ring closing metathesis are the key steps involved in the target synthesis.
Stereoselective synthesis of (+)-diplodialides-B, C and a formal synthesis of (+)-diplodialide-A by ring-closing metathesis approach
Sharma,Reddy, K. Laxmi
, p. 3197 - 3202 (2007/10/03)
Stereoselective synthesis of diplodialides-B and C and the formal synthesis of diplodialide-A are reported. A combination of Jacobsen's hydrolytic kinetic resolution and Sharpless epoxidation is used for the creation of two stereogenic centers, while a ring-closing metathesis strategy was used for the construction of the lactone ring.
