92960-08-2

Upstream product

• 108-36-1 1,3-dibromobenzene 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 19920-85-5 1-(3-bromophenyl)cyclohexanol 

Downstream Products

• 83777-43-9 2-(3-biphenilyl)-m-quaterphenyl 
• 98905-03-4 3-bromo-1,1′: 3′1″-terphenyl 
• 13975-06-9 3.3''''-Dibrom-m-quinquiphenyl 

Relevant academic research and scientific papers

Copper/Selectfluor-System-Catalyzed Dehydration-Oxidation of Tertiary Cycloalcohols: Access to β-Substituted Cyclohex-2-enones, 4-Arylcoumarins, and Biaryls

A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols. Thus, by using 2 equiv. of Selectfluor at 25 C, the dehydration-oxidation of tertiary cyclohexanols and oxabenzocyclohexanols gave β-substituted cyclohex-2-enones and 4-arylcoumarins, respectively; whereas the dehydration-oxidation of tertiary cyclohexanols gave biaryls as the final products by using 2.5 equiv. of Selectfluor at 80 C. A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols.

COMPOUNDS AND USES THEREOF IV

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer D