92975-67-2Relevant academic research and scientific papers
Acylzirconocene chloride as an 'unmasked' acyl anion
Harada, Susumu,Taguchi, Takeo,Tabuchi, Nobuhito,Narita, Kensuke,Hanzawa, Yuji
, p. 1696 - 1698 (2007/10/03)
Under mild conditions the acyl group of acylzirconocene chloride 1 formed from an alkene or alkyne and [(C5H5)H2ZrHCl] reacts as an 'unmasked' acyl anion. The Lewis acid mediated reactions with aldehydes that yield α-ketol products in high yields demonstrate the versatility of this reagent for C - C coupling.
REACTIONS OF ACYL ANIONS GENERATED FROM ACID CHLORIDES AND DIIODOSAMARIUM
Souppe, J.,Namy, J-L.,Kagan, H.B.
, p. 2869 - 2872 (2007/10/02)
Acid chlorides react with SmI2 to give α-diketones.Various experiments show that the initially formed acyl radical is rapidly transformed into an acyl anion which is thus generated by quite an unusual route.This species acylates acid chlorides, aldehydes and ketones in situ to give α-diketones and α-diketols.There are some limitations to this acyl anion chemistry but the reactions are realized with a good efficiency at room temperature in THF solution.
