92981-78-7

Basic information

• Product Name: 2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride
• Synonyms: Tesmilifene hydrochloride; BMY-33419; BMS-217380; N,N-DPPE; 2-(4-benzylphenoxy)-N,N-diethylethanamine hydrochloride (1:1)
• CAS NO: 92981-78-7
• Molecular Formula: C₁₉H₂₅NO*ClH
• Molecular Weight: 319.8688
• EINECS: 216-769-2
• Mol File: 92981-78-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 397°C at 760 mmHg
• Flash Point: 116.8°C
• Vapor Pressure: 1.64E-06mmHg at 25°C
• CAS DataBase Reference: 2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride(92981-78-7)
• EPA Substance Registry System: 2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride(92981-78-7)

Safety Data

• Hazardous Substances Data: 92981-78-7(Hazardous Substances Data)

Upstream product

• 101-53-1 p-benzylphenol 
• 869-24-9 2-chloro-N,N-diethylethylamine hydrochloride 
• 100-35-6 2-(diethylamino)ethyl chloride 

Relevant articles and documents

Synthesis of a tritium labelled antihistaminic drug [3H]-N,N-diethyl-2-[4-(phenylmethyl)phenoxy]-ethaneamine · HCl

A tritium labelled antihistamine, N,N-diethyl-2-[4-[phenylmethyl)phenoxyl- ethaneamine · HCl (DPPE, 4) was synthesized to investigate its binding characteristics intracellular histamine receptors (H(IC)) and for further studies with specific ligands of H(IC) to determine their potential effects on cell proliferation. A palladium catalyzed reduction of an activated carbonyl between the two phenyl groups of N,N-diethyl-2-[4(benzoyl)phenoxy]-ethaneamine · HCl (DBPE, 3) with 100% tritium gas was successful, where 55% of the theoretical activity (specific activity 31.6 Ci/mmol) was obtained.