929872-80-0

Basic information

• Product Name: N-Boc-D-tyrosine N'-methoxy-N'-methylamide
• Synonyms: N-Boc-D-tyrosine N'-Methoxy-N'-MethylaMide;Carbamic acid, N-[(1R)-1-[(4-hydroxyphenyl)methyl]-2-(methoxymethylamino)-2-oxoethyl]-, 1,1-dimethylethyl ester
• CAS NO: 929872-80-0
• Molecular Formula: C16H24N2O5
• Molecular Weight: 324.377
• Mol File: 929872-80-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 110 - 112 °C
• CAS DataBase Reference: N-Boc-D-tyrosine N'-methoxy-N'-methylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-D-tyrosine N'-methoxy-N'-methylamide(929872-80-0)
• EPA Substance Registry System: N-Boc-D-tyrosine N'-methoxy-N'-methylamide(929872-80-0)

Safety Data

• Hazardous Substances Data: 929872-80-0(Hazardous Substances Data)

Upstream product

• 70642-86-3 N-(tert-butoxycarbonyl)-D-tyrosine 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1012341-50-2 (2R,4S)-5-[(1,1‘-biphenyl)-4-yl]-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid 
• 149709-61-5 (2S,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid ethyl ester 
• 149709-58-0 (R)-α-<<(1,1-dimethylethoxy)carbonyl>amino><1,1'-biphenyl>-4-propanal 
• 1383027-39-1 C₁₇H₂₃F₃N₂O₇S 
• 929872-79-7 C₂₃H₃₅N₃O₆Si 
• 929872-82-2 2-(trimethylsilyl)ethyl (4R)-4-[tert-butoxycarbonyl(methyl)amino]-5-(4-methoxyphenyl)-3-oxopentanoate 

Relevant articles and documents

An effective route to (-)-aphanorphine using D-tyrosine as a chiral building block

A stereoselective approach toward a naturally occurring alkaloid, (-)-aphanorphine, has been achieved via a series of reactions from Boc-D-tyrosine. Georg Thieme Verlag Stuttgart.

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.