93073-20-2Relevant articles and documents
Microwave-enhanced reactions of 4-amino-5-merecapto-1,2,4-triazoles with benzoyl chloride and aromatic aldehydes
Bai, Yinjuan,Zhao, Guifang,Li, Chunyuan,Zhao, Shuixia,Shi, Zhen
, p. 3311 - 3319 (2008/12/22)
The microwave-enhanced reactions of 4-amino-5-mercapto-3-substituent-1,2,4- triazoles with benzoyl chloride or arylaldehydes under solvent-free conditions without catalyst were studied. 3-Substituded-6-phenyl-1,2,4-triazolo[3,4-b]-1,3, 4-thiadiazoles were
3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: Synthesis, antimicrobial and antiviral activity. II
Invidiata,Simoni,Scintu,Pinna
, p. 659 - 664 (2007/10/03)
A series of novel 3,6-disubstituted 1,2,4-triazolo[3,4-b] [1,3,4]thiadiazole derivatives was prepared and tested to evaluate their antimycotic and antibacterial activities. Anti-HIV-1 activity has also been investigated. Among the test compounds, derivatives 10a-14a and 16c showed anti-HIV-1 activity at concentrations slightly below those cytotoxic. Substitutions at 3 and 6 positions seems to be important in lowering the cytotoxicity of compounds.
Synthesis and Pharmacology of 2-Aryl/aralkyl-5-aryl/aralkyl/diaralkyl-s-triazolo-1,3,4-thiadiazoles
Deshmukh, A. A.,Mody, M. K.,Ramalingam, T.,Sattur, P. B.
, p. 793 - 795 (2007/10/02)
A series of s-triazolo-1,3,4-thiadiazoles (III) carrying aryl or aralkyl group at 2-position and aryl, aralkyl or diaralkyl group at 5-position have been synthesised and evaluated for their biological activities.Some of the compounds exhibit strong CNS depressant and mild to moderate antiinflammatory action in experimental animals.