1807455-76-0Relevant articles and documents
A [...] related substance diamine synthesis method
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, (2018/09/12)
The invention relates to a rivaroxaban related substance diamine which can be used as a reference substance to research and control rivaroxaban. The preparation method is simple, and the raw materials are easily available. The structural formula of the diamine is shown as follows: FORMULA shown in the description and the formula is C25H24CL2N4O4S2, and the molecular weight is 610.5. The rivaroxaban related substance diamine provided by the invention can be used as a reference substance for monitoring impurities of the rivaroxaban. The synthetic method for the rivaroxaban related substance diamine provided by the invention is simple to operate, has excellent practicality, and can bringrelatively good economic and social benefits.
Rivaroxaban impurities and preparing method and application thereof
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Paragraph 0060, (2017/08/28)
The invention discloses rivaroxaban impurities. The rivaroxaban impurities include the rivaroxaban impurity 6, the rivaroxaban impurity 10, the rivaroxaban impurity 11 and the rivaroxaban impurity 12; in addition, the invention discloses a preparing method and application of the rivaroxaban impurities. By means of the rivaroxaban impurities and the preparing method thereof, the basis is consolidated for rivaroxaban midbodies and raw material medicine and quality researching of compositions of the rivaroxaban impurities. The structural formula is shown in the specification.