931386-67-3Relevant academic research and scientific papers
Copper-catalyzed three-component formal [3 + 1 + 2] annulations for the synthesis of 2-aminopyrimidines fromO-acyl ketoximes
Chen, Hongbiao,Deng, Guo-Jun,Huang, Huawen,Xu, Zhenhua
supporting information, p. 8706 - 8710 (2021/10/22)
A copper-based catalytic system has been developed to enable formal [3 + 1 + 2] annulations of ketoxime acetates, aldehydes, and cyanamides. This protocol offers a new strategy for the synthesis of highly substituted 2-aminopyrimidine compounds, and more importantly, pyrimidines have now been included in the N-heterocycle family constructed usingO-acyl ketoximes as N-C-C synthons.
An efficient route for annulation of pyrimidines to steroids and non-steroids via a base catalyzed one-pot three component reaction
Saikia, Pallabi,Gogoi, Shyamalee,Gogoi, Sanjib,Boruah, Romesh C.
, p. 1 - 6 (2014/07/21)
A facile strategy for the synthesis of steroidal A- and D-ring fused pyrimidines has been accomplished in high yields via a one-pot reaction of steroidal ketones, aromatic aldehydes and amidine derivatives in presence of potassium tert-butoxide in refluxi
