93188-01-3

Usage

Uses

Used in Pharmaceutical Industry:
BENZYL 2-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE is used as a key intermediate in the synthesis of pharmaceutical agents, primarily for the development of drugs targeting neurodegenerative diseases and mental health conditions. Its structural properties allow for the creation of molecules with specific therapeutic effects, making it an invaluable component in medicinal chemistry.
Used in Agriculture Products:
In the agricultural sector, BENZYL 2-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE is utilized as a component in the formulation of various agricultural products. Its role may involve enhancing the effectiveness of pesticides or contributing to the development of novel plant growth regulators, thereby improving crop yields and resistance to diseases.
Used in Materials Science:
BENZYL 2-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE also finds applications in materials science, where it may be employed in the design and synthesis of new materials with unique properties. Its incorporation into polymers or other materials could lead to advancements in areas such as drug delivery systems, sensors, or novel therapeutic agents.
Overall, BENZYL 2-CARBAMOYLPYRROLIDINE-1-CARBOXYLATE is a multifaceted chemical entity with broad applications across different industries, underpinning its importance in modern scientific and technological advancements.

InChI:InChI=1/C13H16N2O3/c14-12(16)11-7-4-8-15(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H2,14,16)

Upstream product

• 1148-11-4 N-carbobenzyloxyproline 
• 501-53-1 benzyl chloroformate 
• 2812-47-7 pyrrolidine-2-carboxylic acid amide 

Downstream Products

• 57734-44-8 1-benzyl-2-aminomethyl-pyrrolidine 
• 60169-70-2 1-benzylpyrrolidine-2-carboxamide 
• 119020-06-3 (±)-benzyl 2-cyanopyrrolidine-1-carboxylate 
• 2812-47-7 pyrrolidine-2-carboxylic acid amide 
• 5768-79-6 tetrahydropyrrolo[1,2-c]imidazol-1,3-dione 
• 113586-10-0 Z-Pro-Δ Val 
• 113586-06-4 (Z)-Z-Pro-Δ Abu 
• 113586-17-7 (E/Z)-Z-Pro-Δ Ile 

Relevant academic research and scientific papers

INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS

The present invention relates to compounds and methods useful as inhibitors of nitric oxide synthase. Certain compounds of the subject invention have the following structural formula: wherein T, X, and Y are independently selected from the group consisting of CR4, N, NR4, S, and O; U is selected from the group consisting of CR10 and N; V is selected from the group consisting of CR4 and N; W and W' are independently selected from the group consisting of CH2, CR7R8, NR9, O, N(O), S(O)q and C(O); n, m and p are independently an integer from 0 to 5; q is 0, 1, or 2; and other substituents are as defined herein. Other compounds of the subject invention have structural formulas as defined herein. Also disclosed herein are pharmaceutical compositions comprising the compounds of the subject invention

Catalytic epoxidation of unfunctionalized alkenes by dinuclear nickel(II) complexes

The synthesis, crystal and molecular structure and catalytic activity in epoxidation reactions of new dinuclear nickel(II)-complexes, octahedral μ-diacetato-μ-[2,6-bis[N-2-2'-pyridylethyl)formimidoyl]phenolato]bis nickel(II)·perchlorate·methanol (6) and square planar (μ-hydroxo-μ-[2,6-bis[N-((S)-1-benzyl-2-yl-pyrrolidine)formimidoyl]p henolato]bisnickel(II)·bisperchlorate (7), are described. For the preparation of 7 a new 5-step route for homochiral bisamine (S)-benzyl-2-aminomethyl-pyrrolidine (19) was developed starting from (S)-proline. Epoxidation of unfunctionalized alkenes with sodium hypochlorite and tert-butyl hydroperoxide as terminal oxidants was effectively catalyzed with bisnickel(II)-complexes 6 and 7, and a turnover of 165 was reached using trans-β-methylstyrene (34). The epoxidations probably proceed via a radical intermediate (such as OCl·) and no enantioselectivity is obtained under phase transfer conditions. In epoxidation reactions employing tert-butyl hydroperoxide as terminal oxidant a turnover of 43 was obtained with trans-stilbene (30) as substrate. Unexpectedly in the case of styrene (29) 1,2-bis-(tert-butylperoxy)ethylbenzene (59) was isolated as the major product.