932015-08-2

Upstream product

• 10022-13-6 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 
• 1308293-04-0 ethyl 6-O-acetyl-3,4-di-O-benzoyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 
• 34637-22-4 3-[(N-benzyloxycarbonyl)amino]propanol 
• 933790-89-7 ethyl 3,4-di-O-benzoyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 
• 933790-88-6 ethyl 3,4-di-O-benzoyl-2-deoxy-2-phthalimido-1-thio-6-O-trityl-β-D-glucopyranoside 
• 130539-43-4 ethyl 2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 
• 99409-32-2 ethyl-3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 
• 31505-42-7 2-(2-carboxybenzamido)-2-deoxy-D-glucopyranose 
• 933790-97-7 C₃₀H₂₄NO₉Br 
• 933790-96-6 6-O-acetyl-1,3,4-tri-O-benzoyl-2-deoxy-2-phthalimido-α-D-glucopyranose 
• 933790-95-5 1,3,4-tri-O-benzoyl-2-deoxy-2-phthalimido-α-D-glucopyranose 

Relevant academic research and scientific papers

ANTIMICROBIAL VACCINE COMPOSITIONS

This invention is directed to antimicrobial vaccine compounds and compositions comprising oligosaccharide β-(1→6)- glucosamine groups having from 3 to 12 glucosamine units linked through a linker group to tetanus toxoid wherein the toxoid is primarily in

LOW CONTAMINANT ANTIMICROBIAL VACCINES

Disclosed are antimicrobial vaccines comprising oligosaccharide β-(1→6)-glucosamine groups.

METHODS FOR PROVIDING CONTINUOUS THERAPY AGAINST PNAG COMPRISING MICROBES

Disclosed are antimicrobial vaccines comprising oligosaccharide β-(1→6)-glucosamine groups.

Methods for inhibiting biofilm formation

Disclosed are methods and kits of parts useful in inhibiting biofilm formation in vivo in subjects at risk of developing biofilms. These methods include inhibiting biofilm formation where the extracellular matrix in the biofilm includes poly-β-(1→6)glucos

The study of the reaction of terminated oligomerization in the synthesis of oligo-(β1-6)-glucosamines

The applicability of terminated oligomerization to the synthesis of oligo-(β1-6)-glucosamines, fragments of the intercellular polysaccharide adhesin of staphylococci, was studied. The reactions of terminated oligomerization were carried out with mono-, di-, and trisaccharide monomers and N-protected aminopropanol; and spacered mono-and disaccharides as terminating molecules were also attempted. The primary formation of cyclic products of monomer intramolecular glycosylation was observed in almost all the reactions. Only the experiments with the monomer based on the disaccharide bromide under the conditions of the Helferich reaction led to reduced yields (30%) of the cyclic products. However, even in this case, the desired terminated oligosaccharides were generated in approximately 10% yield and mainly were the products of single glycosylation of the terminator by the monomer. These experiments allow the conclusion that, under the examined conditions, the reaction of terminated oligomerization could not result in the synthesis of oligoglucosamines with a high molecular mass. Pleiades Publishing, Inc., 2006.