932017-92-0

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 352647-05-3 3-(adamantan-1-yl)-4-hydroxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 768-95-6 1-adamanthanol 
• 100-44-7 benzyl chloride 

Downstream Products

• 932017-93-1 ethyl (E)-3-(3-(adamantan-1-yl)-4-benzyloxyphenyl)acrylate 
• 932017-96-4 ethyl 3'-(adamantan-1-yl)-4'-benzyloxy-2-(3-(1,3-dioxoisoindolin-2-yl)propoxy)biphenyl-4-carboxylate 
• 932017-91-9 (3E,5E)-6-(3-(adamantan-1-yl)-4-benzyloxyphenyl)-3-(ethoxycarbonyl)hexa-3,5-dienoic acid 
• 932017-89-5 ethyl 3'-(adamantan-1-yl)-4'-benzyloxy-2-hydroxybiphenyl-4-carboxylate 
• 932017-94-2 (E)-3-(3-(adamantan-1-yl)-4-benzyloxyphenyl)prop-2-en-1-ol 
• 932017-95-3 (E)-3-(3-(adamantan-1-yl)-4-benzyloxyphenyl)acrylaldehyde 

Relevant academic research and scientific papers

Discovery of new chalone adamantyl arotinoids having RXRα-modulating and anticancer activities

In the present study, a new series of chalcone adamantly arotinoids (chalcone AdArs) derived from RAR antagonist MX781, are synthesized, characterized, and evaluated for the biological activities in vitro. The studies of antiproliferative activity and RXR

Type-I flavone derivative as well as preparation method and application thereof

The invention discloses a type-I flavone derivative as well as a preparation method and application thereof, and relates to a flavone derivate. The preparation method comprises the following steps: sequentially preparing 2,4-dyhydroxy-5-(1-adamantyl)-acet

New synthetic approach to atypical retinoids: application of a versatile annulation procedure

A new approach to an atypical retinoid is presented. The C15 skeleton was built up by exploiting a step-by-step sequence: the C9 fragment of an intermediate was homologated by reaction with a C4 phosphorane, and then submitted to a benzannulation reaction. The last two carbon atoms were inserted by a Wittig reaction with the C2 phosphorane of ethyl bromoacetate. Manipulation of functional groups was then performed.