93232-29-2

Usage

Uses

Used in Organic Synthesis:
Ethanone, 1,1'-([1,1':2',1''-terphenyl]-4,4''-diyl)bisis used as a building block in the synthesis of various organic compounds due to its unique molecular structure.
Used in Materials Science:
Ethanone, 1,1'-([1,1':2',1''-terphenyl]-4,4''-diyl)bisis used in the development of new materials, taking advantage of its bis-phenyl compound structure.
Used in Pharmaceutical Industry:
Ethanone, 1,1'-([1,1':2',1''-terphenyl]-4,4''-diyl)bishas potential applications in the pharmaceutical field, although the specific uses are not detailed in the provided materials.
Used in Dyes and Pigments Production:
Ethanone, 1,1'-([1,1':2',1''-terphenyl]-4,4''-diyl)bisis also used in the production of dyes and pigments, likely due to its yellowish crystalline solid appearance and chemical properties.

Upstream product

• 84-15-1 o-terphenyl 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 269410-07-3 1,2-bis(4,4,5,5-tetramethyl-[1,3,2]dioxabororan-2-yl)benzene 
• 13329-40-3 4-Iodoacetophenone 

Relevant academic research and scientific papers

A New Tetradentate β-Diketonate-Europium Chelate That Can Be Covalently Bound to Proteins for Time-Resolved Fluoroimmunoassay

A new chlorosulfonylated tetradentate β-diketone, 4,4′-bis(1″,1″,1″,2″,2″,3″,3″- heptafluoro-4″,6″-hexanedion-6″-y1)chlorosulfo-o-terphenyl (BHHCT), was synthesized as a chelating label for Eu3+. BHHCT can be covalently bound to proteins under mild conditions and forms a strongly fluorescent chelate with Eu3+. Bovine serum albumin (BSA) and streptavidin (SA) were labeled with BHHCH-Eu3+, and the latter was used for time-resolved fluoroimmunoassay of a-fetoprotein (AFP) in human sera. A remarkably high sensitivity was obtained, with a detection limit of 4.1 × 10-3 pg/mL, which corresponds to an improvement of about 4-5 orders of magnitude, compared to those of all conventional immunoassays including fluoroimmunoassay, enzyme immunoassay, and radioimmunoassay. The high sensitivity has been attained both by strong fluorescence of the present label and by the extremely suppressed background level brought about by the direct labeling of proteins with the β-diketone-Eu3+ complex. A general consideration and ideas are given for designing ideal label ligands for strongly fluorescent Eu3+ complexes.

LUMINESCENT BIOMOLECULAR COMPLEX AND USE THEREOF

The technology relates to biomolecular complex having an antibody-binding protein; a polypeptide linker capable of receiving a luminescence-activating unit; and a luminescence- activating unit. Also disclosed is the use of the biomolecular complex to detect biological target entities.

A novel biocompatible europium ligand for sensitive time-gated immunodetection

We describe the synthesis of a novel hydrophilic derivative of a tetradentate β-diketone europium ligand that was used to prepare an immunoconjugate probe against Giardia lamblia cysts. We used a Gated Autosynchronous Luminescence Detector (GALD) to obtain high quality delayed luminescence images of cells 30-fold faster than ever previously reported.

Platinum-catalysed diborylation of arynes: Synthesis and reaction of 1,2-diborylarenes

Arynes are found to be facilely inserted into bis(pinacolato)diboron by using a platinum-isocyanide catalyst, affording diverse 1,2-diborylarenes, which can be converted into o-terphenyls via Suzuki-Miyaura coupling reaction.

Assay of substance in biological sample using labeled probe

A method for analyzing an objective substance, comprsing reacting a labeled probe with an objective substance on a biological sample, said probe comprsing a label substance of the formula (I): wherein A1is an aromatic group, R1is a hydrogen or —COCH2COCnF2n+1and n is an integer of 1-6, which is bonded to a probe selected from the group consisting of nucleic acid, nudeic acid binding potein, low molecular ligand and receptor for ligand (except antibody) to give a fluorescent complex, reacting the complex with an objective substance on a biolgical sample and assaying fluorescence of the resultant fluorescent complex, a labeled nucleic acid probe and a labeled nucleotide. According to the method of the present invention, defects such as hindrance of fluorescence due to contaminant substance, low sensitivity and the like can be resolved, thereby enabling analysis on a tissue.