93264-47-2

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Pyrrolidin-1-yl-butan-1-ol is utilized as a building block in the creation of pharmaceutical drugs. Its unique structure allows it to be a key component in the development of new medications.
Used as a Solvent:
In various chemical processes, 4-Pyrrolidin-1-yl-butan-1-ol is employed as a solvent. Its ability to dissolve a wide range of substances makes it a versatile component in the chemical industry.
Used in Organic Synthesis:
4-PYRROLIDIN-1-YL-BUTAN-1-OL also serves as a reagent in organic synthesis, where it aids in the formation of complex organic molecules through chemical reactions.
Used in Medicinal Chemistry:
4-Pyrrolidin-1-yl-butan-1-ol has potential applications in the field of medicinal chemistry, especially in the development of drugs that target central nervous system disorders. Its unique properties make it a promising candidate for creating effective treatments.

InChI:InChI=1/C8H17NO/c10-8-4-3-7-9-5-1-2-6-9/h10H,1-8H2

Upstream product

• 110-63-4 Butane-1,4-diol 
• 73200-24-5 4-hydroxy-1-(pyrrolidin-1-yl)butan-1-one 
• 767-10-2 1-butylpyrrolidine 

Downstream Products

• 101889-07-0 4-(pyrrolidinobutyl)3,4,5-trimethoxybenzoate 
• 102466-13-7 3,4,5-trimethoxy-trans-cinnamic acid-(4-pyrrolidino-butyl ester) 
• 193963-46-1 (4-[4-(1-pyrrolidinyl)butoxy]phenyl)-(2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]-thiophen-3-yl)ketone 
• 1158803-51-0 4-(pyrrolidin-1-yl)butyl 2-(4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)phenyl)acetate 
• 7255-63-2 1-(3-buten-1-yl)pyrrolidine 

Relevant academic research and scientific papers

Steric effects in the catalytic amination of γ-, δ-, and ε-glycols

The amination of butane-1,4-diol, isomeric dipropylene glycols, and cyclohexane-1,4-diyldimethanol in the presence of nickel/copper/chromium catalysts has been studied. The effect of the initial glycol structure on the reaction selectivity has been estima

Platinum-Catalyzed, Terminal-Selective C(sp3)-H Oxidation of Aliphatic Amines

This Communication describes the terminal-selective, Pt-catalyzed C(sp3)-H oxidation of aliphatic amines without the requirement for directing groups. CuCl2 is employed as a stoichiometric oxidant, and the reactions proceed in high yield at Pt loadings as low as 1 mol%. These transformations are conducted in the presence of sulfuric acid, which reacts with the amine substrates in situ to form ammonium salts. We propose that protonation of the amine serves at least three important roles: (i) it renders the substrates soluble in the aqueous reaction medium; (ii) it limits binding of the amine nitrogen to Pt or Cu; and (iii) it electronically deactivates the C-H bonds proximal to the nitrogen center. We demonstrate that this strategy is effective for the terminal-selective C(sp3)-H oxidation of a variety of primary, secondary, and tertiary amines.

Catalytic hydrogenation of amides to amines under mild conditions

Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright

SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLES OF AN IRON CATALYST. 2. THE CONVERSIONS OF 1,4-BUTANEDIOL AND DIETHYLENEGLYCOL IN THE PRESENCE OF AMMONIA AND HYDROGEN

The gas-phase interaction of 1,4-butanediol and diethylene glycol with ammonia and/or hydrogen on a reduced, fused, iron catalyst has been investigated.