7255-63-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-Butenyl)pyrrolidine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form complex molecular structures that can target specific biological pathways.
Used in Agrochemical Industry:
1-(3-Butenyl)pyrrolidine is used as a precursor in the development of agrochemicals to create compounds that can effectively manage pests and diseases in agriculture.
Used in Organic Chemistry Research:
1-(3-Butenyl)pyrrolidine is used as a building block in organic chemistry for exploring new reactions and developing innovative synthetic routes to create novel organic substances with potential applications in various fields.

InChI:InChI=1/C8H15N/c1-2-3-6-9-7-4-5-8-9/h2H,1,3-8H2

Upstream product

• 857423-51-9 acetic acid-(4-pyrrolidino-butyl ester) 
• 16450-38-7 5-azoniaspiro<4.4>nonane bromide 
• 180890-82-8 N-(3-bromo-3-butenyl)pyrrolidine 
• 109-99-9 tetrahydrofuran 
• 7664-41-7 ammonia 
• 123-75-1 pyrrolidine 
• 50-00-0 formaldehyd 
• 106-95-6 allyl bromide 
• 93264-47-2 4-(pyrrolidin-1-yl)butan-1-ol 
• 874528-56-0 bis-tetrahydro[2]furyl-amine 
• 79448-06-9 4,4’-azanediylbis(butan-1-ol) 
• 5162-44-7 1-bromo-4-butene 
• 110-63-4 Butane-1,4-diol 

Relevant academic research and scientific papers

Barbier-type allylation of iminium ions generated in situ in aqueous medium

Iminium ions, generated in aqueous solution from secondary amines and formaldehyde, undergo a Barbier-type allylation mediated by tin, aluminum and zinc. The reaction is catalyzed by copper and produces tertiary homoallylamines in up to 85% yield.

One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts

The synthesis of 1-butylpyrrolidine and its derivatives (1-butylpyrrolidine with a little of 1-butenylpyrrolidines) was developed via a one-pot method from ammonia and 1,4-butandiol. Here, the product of 1-butylpyrrolidine was emphatically investigated, and the yield was 76% under the optimized conditions. Such a route was realized through successive N-alkylation using aqueous ammonia as the nitrogen source over the CuNiPd/ZSM-5 catalyst, which was prepared by a simple incipient wetness method. In this route, 1,4-butandiol not only participated in the formation of the N-heterocycle, but also acted as an alkylating reagent. This work offers a straightforward, economical route for 1-butylpyrrolidine and its derivatives. This journal is

Thienopyridones as AMPK activators for the treatment of diabetes and obesity

The present invention relates to compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders such as diabetes, metabolic syndrome, and obesity.

The synthesis of (±)-heliotridane and (6S,7S)-dihydroxyheliotridane via sequential hydrogen atom abstraction and cyclisation

Treatment of N-(3-bromo-3-butenyl)pyrrolidine derivatives with tributyltin hydride and AIBN leads to hydrogen atom transfer of the intermediate vinyl radicals to give α-amino radicals which then cyclise stereoselectively yielding pyrrolizidines 1 and 13.