932744-55-3

Upstream product

• 932744-54-2 C₄₂H₆₆N₈O₁₃ 
• 870487-73-3 (2-aminoethyl)-L-valine tert-butyl ester 
• 870487-72-2 (2-(((benzyloxy)carbonyl)amino)ethyl)-L-valine tert-butyl ester 
• 870487-74-4 C₂₆H₃₄N₂O₄ 
• 756525-99-2 3-[2-[2-[2-[[3-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-propionylamino]ethoxy]ethoxy]ethoxy]ethoxy]propionic acid-2,5-dioxo-pyrrolidin-1-yl ester 
• 1037794-89-0 C₂₄H₄₀N₆O₅ 
• 870487-75-5 C₂₂H₂₆N₂O₄*ClH 
• 1037794-82-3 C₁₇H₂₆N₄O₄ 
• 932744-52-0 C₃₂H₃₆N₄O₆ 
• 932744-53-1 C₃₉H₅₀N₆O₇ 
• 18144-47-3 tert-butyl 4-aminobenzoate 
• 133174-15-9 (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-ureidopentanoic acid 

Downstream Products

• 1037796-55-6 C₆₈H₈₆BrN₁₃O₁₅ 
• 932744-58-6 C₆₆H₈₄BrN₁₃O₁₅ 

Relevant academic research and scientific papers

CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates that are potent cytotoxins and include a linker between the drug and ligand where the linker has a single amino acid. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.