932744-52-0

Upstream product

• 18144-47-3 tert-butyl 4-aminobenzoate 
• 133174-15-9 (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-ureidopentanoic acid 

Downstream Products

• 1049811-88-2 Fmoc-Cit-PABA 
• 1037794-82-3 C₁₇H₂₆N₄O₄ 
• 1037795-42-8 C₃₀H₄₁N₇O₈ 
• 1037795-38-2 C₃₄H₄₉N₇O₈ 
• 932744-53-1 C₃₉H₅₀N₆O₇ 
• 1049811-92-8 C₄₁H₄₄BrN₉O₆ 
• 932744-55-3 C₃₈H₅₈N₈O₁₃ 
• 1049812-54-5 C₄₃H₄₆ClN₉O₆ 
• 932744-54-2 C₄₂H₆₆N₈O₁₃ 
• 1049811-94-0 C₅₁H₅₅BrN₁₀O₉ 
• 1049812-57-8 C₂HF₃O₂*C₅₃H₅₇ClN₁₀O₉ 
• 1037795-30-4 C₃₇H₄₅N₅O₇ 
• 1037794-89-0 C₂₄H₄₀N₆O₅ 
• 1037795-34-8 Boc-L-valine-L-citrulline-p-aminobenzoic acid t-butyl ester 

Relevant academic research and scientific papers

CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates that are potent cytotoxins and include a linker between the drug and ligand where the linker has a single amino acid. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.