93286-94-3Relevant academic research and scientific papers
REACTIONS OF 1-VINYLBENZIMIDAZOLE-2-THIONE WITH ALCOHOLS AND PHENOL
Abramova, N. D.,Skvortsova, G. G.,Trzhtsinskaya, B. V.
, p. 656 - 658 (1984)
1-(α-Alkoxyethyl)- and 1-(α-phenoxyethyl)benzimidazole-2-thiones were obtained in the reaction of 1-vinylbenzimidazole-2-thione with alcohols and phenol in the presence of gaseous hydrogen chloride.It was established that partial hydrolysis of the 1-(α-alkoxyethyl)benzimidazole-2-thiones to benzimidazole-2-thione with subsequent alkylation with excess alcohol at the exocyclic sulfur atom occurs under the conditions of the investigated reaction.A convenient method for the alkylation of thiones was proposed, and a number of 2-alkylthiobenzimidazoles were synthesized.
