93355-74-9Relevant academic research and scientific papers
New approaches for the synthesis of 1,3,4-thiadiazole and 1,2,4-triazole derivatives with antimicrobial activity
Wardakhan, Wagnat W.,El-Sayed, Nahed N. E.
experimental part, p. 790 - 804 (2009/10/15)
The thiosemicarbazide derivatives 3a and 3b were cyclized in the presence of concentrated sulfuric acid to give the 5-cyanomethyl-1,3,4-thiadiazole derivatives 4a and 4b, respectively. The latter products were used for many heterocyclic transformations to
Activated nitriles in heterocyclic synthesis. Part 6: Novel synthesis of thiadiazolo pyridine derivatives
Sowellum, S. Z. A.,Khodeir, M. N. M.,El-Amin, S. M.,Elagamey, A. A.
, p. 533 - 534 (2007/10/02)
Several new thiadiazolo pyridine, thiazole and coumarin derivatives were synthesized via the reaction of 2-cyanomethylthiadiazole with cinnamonitriles, mercaptoacetic acid and salicylaldehyde.
The Reaction of Isothiocyanates with 2-Cyanoethanoic Acid Hydrazide. A Novel Synthesis of 1,3,4-Thiadiazoles
Elmoghayar, Mohamed Rifaat Hamza,Abdalla, Sanaa Osman,Nasr, Mohamed Yousry Abdel-Samad
, p. 781 - 784 (2007/10/02)
Benzoyl and ethoxycarbonyl isothiocyanates reacted with 2-cyanoethanoic acid hydrazide 2 to afford 1-cyanoacetyl-4-substituted thiosemicarbazide (5a,b).Compound 5a afforded the pyrazolo-s-triazine derivative 6 on treatment with 5percent potassium h
