933768-06-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Ethynyl-2-fluoropyridine is used as a building block for the synthesis of various pharmaceuticals due to its versatile reactivity and ability to participate in a wide range of chemical reactions. It contributes to the development of novel compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Ethynyl-2-fluoropyridine is utilized as a building block for the synthesis of agrochemicals, such as pesticides and herbicides, due to its unique chemical properties and reactivity.
Used in Functional Materials:
3-Ethynyl-2-fluoropyridine is employed in the synthesis of functional materials, which have specific properties and applications in various fields, such as electronics, sensors, and advanced materials.
Used as a Reagent in Organic Synthesis:
3-Ethynyl-2-fluoropyridine serves as a reagent in organic synthesis, particularly in research laboratories, for the preparation of novel compounds with potential biological activities.
Used in Medicinal Chemistry for Drug Discovery and Development:
3-Ethynyl-2-fluoropyridine is considered a valuable tool in the field of medicinal chemistry, where it aids in drug discovery and development processes by providing a versatile and reactive building block for the creation of new pharmaceutical compounds.

Upstream product

• 207602-10-6 2-fluoro-3-[(trimethylsilyl)ethynyl]pyridine 
• 113975-22-7 2-fluoro-3-iodopyridine 

Downstream Products

• 132643-80-2 2-phenyloxepino[2,3-b]pyridine 
• 1196079-52-3 1-(4-methylphenyl)-1H-pyrrolo[2,3-b]pyridine 
• 271-63-6 7-Azaindole 
• 272-01-5 furo<2,3-b>pyridine 

Relevant academic research and scientific papers

Rhodium-Catalyzed Direct Arylation of Furopyridine: Synthesis and the Cardiac Effects of Dictamnine Derivatives

Herein is reported a Rh2(OAc)4/IMes ? HCl system that promotes the chemoselective installation of aryl groups at the 2-position of furo[2,3-b]pyridine (53–94% yields). The method is applicable to the direct modification of the natura

Synthesis of indoles, benzofurans, and related heterocycles via an acetylene-activated SNAr/intramolecular cyclization cascade sequence in water or DMSO

The synthesis of 2-substituted indoles and benzofurans was achieved by nucleophilic aromatic substitution, followed by subsequent 5-endo-dig cyclization between the nucleophile and an ortho acetylene. The acetylene serves the dual role of the electron withdrawing group to activate the substrate for SNAr, and the C1-C2 carbon scaffold for the newly formed 5-membered heteroaromatic ring. This method allows for the bond forming sequence of Ar-X-N/O-C1 to proceed in a single synthetic step, furnishing indoles and benzofurans in moderate to high yields. Since the method is not transition metal mediated, brominated and chlorinated substrates are tolerated, and benzofuran formation can be conducted using water or water-DMSO mixtures as solvent. This journal is

TETRACYCLIC INHIBITORS OF JANUS KINASES

The present invention provides compounds that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.