93381-66-9Relevant academic research and scientific papers
Automated Solution-Phase Synthesis of S-Glycosides for the Production of Oligomannopyranoside Derivatives
Kern, Mallory K.,Pohl, Nicola L. B.
supporting information, (2020/06/08)
Thioglycosides are more resistant to enzymatic hydrolysis than their O-linked counterparts, thereby becoming attractive targets for carbohydrate-based therapeutic development. We report the first development of methods for the site-selective incorporation
Total synthesis of the fully lipidated glycosylphosphatidylinositol (GPI) anchor of malarial parasite Plasmodium falciparum
Ali, Asif,Vishwakarma, Ram A.
experimental part, p. 4357 - 4369 (2010/07/06)
We report a new and convergent strategy for the total synthesis of fully lipidated glycosylphosphatidylinositol (GPI) anchor, the major pro-inflammatory factor of malarial parasite (Plasmodium falciparum). The key features of our approach include, the acc
A new approach to construct full-length glycosylphosphatidylinositols of parasitic protozoa and [4-deoxy-Man-III]-GPI analogues
Ali, Asif,Gowda, D. Channe,Vishwakarma, Ram A.
, p. 519 - 521 (2008/09/18)
A new [2 + 2 + 2] approach to construct GPI molecules through the efficient synthesis of glucosamine-inositol and tetramannose intermediates led to a total synthesis of a GPI-anchor of Trypanosoma cruzi, and also afforded a key intermediate for the synthe
Efficient and practical syntheses of three pentasaccharides core structures corresponding to N-glycans
Du, Yuguo,Zhang, Meimei,Kong, Fanzuo
, p. 1757 - 1763 (2007/10/03)
Three branched pentasaccharide derivatives and one tetrasaccharide were synthesized efficiently. The advantages of this method include a one-pot facile synthesis of 3,6-differentially protected mannose building block and an efficient strategy for oligosac
A practical synthetic method for α- and β-glycosyloxyacetic acids
Mandai, Tadakatsu,Okumoto, Hiroshi,Oshitari, Tetsuta,Nakanishi, Katsuyoshi,Mikuni, Katsuhiko,Hara, Ko-Ji,Hara, Ko-Zo
, p. 129 - 132 (2007/10/03)
Dihydroxylation of allyl 2,3,4-tri-O-benzyl-6-O-tritylglycosides provides diols, the anomers of which can easily be separated by column chromatography in a practical scale. These anomers can be cleanly transformed into α- and β-glycosyloxyacetic acids, respectively, via oxidative cleavage of the diol followed by oxidation.
Highly efficient and practical synthesis of 3,6-branched oligosaccharides.
Du,Zhang,Kong
, p. 3797 - 3800 (2007/10/03)
[reaction: see text] A one-pot formation of the 3- and 6-OH differentially protected sugar synthon was described. A mannopyranosyl pentasaccharide and a glucopyranosyl hexasaccharide were prepared employing this new finding.
SYNTHESIS OF A MODEL, LINEAR D-MANNOPENTAOSE FOR THE NONREDUCING-END SEQUENCE OF THE CELL-SURFACE D-MANNAN OF Escherichia coli, Candida albicans, AND Saccharomyces cerevisiae
Ogawa, Tomoya,Yamamoto, Hisao
, p. 79 - 88 (2007/10/02)
Synthesis, in a regio- and stereocontrolled way, of a linear D-manno-oligosaccharide, namely, O-α-Man-(1--3)-O-α-Man-(1--2)-O-α-Man-(1--2)-α-Man-(1--2)-α-Man, which corresponds to a part of the structure of the cell-surface D-mannan of Escherichia coli, C
