934192-24-2Relevant academic research and scientific papers
PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES
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, (2016/07/27)
The present invention relates to a method for preparing an optically active 4-hydroxy-1,2,3,4-tetrahydroquinoline compound [I], which comprises the steps of: treating a racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline compound represented by general formula [I]: [wherein R 1 represents a hydrogen atom or a protecting group for amino group.] with an enzyme having an ability of selectively or preferentially acylating one enantiomer of the racemic compound [I] in the presence of an acyl donor; and if necessary, subjecting the reaction product to solvolysis.
DERMATITIS REMEDIES
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Page/Page column 14, (2008/12/06)
The present invention is to provide a topical dermatitis treating agent which comprises a pyridine compound represented by the following formula [I]: wherein R1 and R2 each represent a lower alkoxy group, =X- represents a group repre
OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME
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Page/Page column 21-22, (2010/11/26)
Disclosed is a method for producing an optically active cyclic alcohol compound represented by the general formula [I] below, wherein a cyclic ketone compound represented by the general formula [II] below is asymmetrically reduced in the presence of (A) an optically active oxazaborolidine compound and a boron hydride compound, or alternatively in the presence of (B) an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand, and a hydrogen donor. Also disclosed is such an optically active cyclic alcohol compound. [I] (In the formula, the symbol is as defined below.) [II] (In the formula, R represents a hydrogen atom or a protective group of an amino group.)
