934240-31-0

Basic information

• Product Name: CNV1014802 (hydrochloride)
• Synonyms: CNV1014802 (hydrochloride);(2S,5R)-5-(4-((2-Fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide hydrochloride;(5R)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-L-prolinamide hydrochloride;GSK-1014802 hydrochloride;2-Pyrrolidinecarboxamide, 5-[4-[(2-fluorophenyl)methoxy]phenyl]-, hydrochloride (1:1), (2S,5R)-;(5R)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-L-prolinamide HYDROCHLRIDE;CNV1014802(Raxatrigine) hydrochloride;Raxatrigine HCl
• CAS NO: 934240-31-0
• Molecular Formula: C₁₈H₁₉FN₂O₂*ClH
• Molecular Weight: 350.8150032
• Mol File: 934240-31-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• Stability: Hygroscopic
• CAS DataBase Reference: CNV1014802 (hydrochloride)(CAS DataBase Reference)
• NIST Chemistry Reference: CNV1014802 (hydrochloride)(934240-31-0)
• EPA Substance Registry System: CNV1014802 (hydrochloride)(934240-31-0)

Safety Data

• Hazardous Substances Data: 934240-31-0(Hazardous Substances Data)

Usage

Description

CNV1014802 (hydrochloride) is a pharmaceutical compound with potential therapeutic applications in the treatment of neurological disorders.

Uses

Used in Pharmaceutical Industry:
CNV1014802 (hydrochloride) is used as a co-therapy for the treatment of epilepsy and related disorders, aiming to enhance the efficacy of existing treatments and improve patient outcomes.

Upstream product

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• 934584-66-4 1-(tert-butyl) 2-methyl (2S,5R)-5-(4-(benzyloxy)phenyl)pyrrolidine-1,2-dicarboxylate 
• 120186-59-6 (4-(benzyloxy)phenyl)magnesium bromide 
• 6793-92-6 p-benzyloxyphenylbromide 
• 934584-88-0 (2S,5R)-1-tert-butyl 2-methyl 5-(4-(2-fluorobenzyl)oxy)phenylpyrrolidine-1,2-dicarboxylate 
• 934240-38-7 (S)-methyl-5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate 
• 405-24-3 4-((2-fluorobenzyl)oxy)benzoic acid 
• 128982-48-9 methyl 4-(2-fluorobenzyloxy)benzoate 
• 1272317-42-6 1-(4-[2-fluorobenzyloxy]phenyl)-2-propen-1-one 
• 1272317-41-5 4-(2-fluorobenzyloxy)-N-methyl-N-methoxybenzamide 
• 99-76-3 methyl 4-hydroxylbenzoate 

Relevant articles and documents

Preparation method of sodium ion channel blocker CNV1014802 hydrochloride form

The invention relates to the field of pharmaceutical chemicals, in particular to a novel preparation method of sodium ion channel blocker (GSK1014802) CNV1014802 hydrochloride for inhibiting sodium ion internal flow, which is a high-selectivity asymmetric

PROCESS FOR PREPARING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES

Disclosed are processes for preparing α-carboxamide pyrrolidine derivatives, in particular (2S,5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and intermediates for use in said processes along with processes for preparing said intermediate

PROCESS FOR PREPARING ALPHA-CARBOXAMIDE PYROLIDINE DERIVATIVES

The invention relates to a novel process for preparing a-carboxamide pyrrolidine derivatives, in particular (2S, 5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide, and to novel intermediates for use in said process along with processes for pr