93447-77-9

Basic information

• Product Name: ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)
• Synonyms: ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl);ethyl 3-amino-3-thiophen-2-ylpropanoate
• CAS NO: 93447-77-9
• Molecular Formula: C₉H₁₃NO₂S
• Molecular Weight: 235.73096
• Mol File: 93447-77-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)(93447-77-9)
• EPA Substance Registry System: ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)(93447-77-9)

Safety Data

• Hazardous Substances Data: 93447-77-9(Hazardous Substances Data)

Upstream product

• 18389-46-3 3-amino-3-(thiophen-2-yl)propanoic acid 
• 64-17-5 ethanol 
• 98-03-3 thiophene-2-carbaldehyde 
• 1071-46-1 hydrogen ethyl malonate 
• 768356-40-7 ethyl (R)-3-amino-3-(2-thienyl)propanoate 

Downstream Products

• 149519-80-2 Ethyl β-[[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino-]-2-thiophenepropanoate 
• 3270-89-1 (S)-3-amino-3-(2-thienyl)propanoic acid 
• 768356-40-7 ethyl (R)-3-amino-3-(2-thienyl)propanoate 
• 161596-37-8 (S)-β-n-butyl-β-alanine 
• 104883-48-9 3-aminoheptanoic acid 

Relevant articles and documents

Dynamic kinetic resolution of β-amino esters by a heterogeneous system of a palladium nanocatalyst and candida antarctica lipase A

A dynamic kinetic resolution (DKR) of β-amino esters have been developed by the use of a heterogeneous racemization catalyst and an immobilized enzyme that accepts aromatic, heteroaromatic and aliphatic substrates. The reaction conditions were optimized to yield an efficient catalytic system without by-product formation. The products are obtained in 96-99 % ee and high yields. Copyright

Candida antarctica lipase A - A powerful catalyst for the resolution of heteroaromatic β-amino esters

Enantioselective acylations of 3-amino-3-heteroarylpropanoates (ArCH(NH2)CH2CO2Et; Ar=2- or 3-thienyl or -furyl) were performed in the presence of Candida antarctica lipase A. As a result of the excellent chemo- and enantioselectivities (E >100), gram-scale resolutions were carried out in ethyl butanoate. The hydrochloride salts of the unreacted R substrates and the butanamides of the reactive S enantiomers were thus prepared.