ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)

Base Information

• Chemical Name: ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)
• CAS No.: 93447-77-9
• Molecular Formula: C9H13NO2S
• Molecular Weight: 235.73100
• Hs Code.: 2934999090
• Mol file: 93447-77-9.mol

Synonyms:ethyl 3-amino-2-methylpropionate;ethyl (+/-)-3-amino-3-(2-thienyl)propanoate;3-amino-2-methyl-propionicacidethylester;ethyl-3-amino-3-(2-thiophenyl) propanoate;

Chemical Property of ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)

Chemical Property:

• PSA: 80.56000
• LogP: 3.20340

Purity/Quality:

98%min ^*data from raw suppliers

ethyl3-amino-3-thien-2-ylpropanoatehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl)

There total 4 articles about ethyl 3-amino-3-(2-thienyl)propanoate(SALTDATA: HCl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophene-2-carbaldehyde (98-03-3) + hydrogen ethyl malonate (1071-46-1) → ethyl (+/-)-3-amino-3-(2-thienyl)propanoate (93447-77-9)

Guidance literature:

With ammonium acetate; hydrogenchloride; In ethanol;

Reference yield:

ethyl (R)-3-amino-3-(2-thienyl)propanoate (768356-40-7) → ethyl (+/-)-3-amino-3-(2-thienyl)propanoate (93447-77-9)

Guidance literature:

In dibutyl ether; at 70 ℃; for 20h; Inert atmosphere;

DOI:10.1002/ejoc.201001714

Reference yield:

ethyl (+/-)-3-amino-3-(2-thienyl)propanoate hydrochloride → ethyl (+/-)-3-amino-3-(2-thienyl)propanoate (93447-77-9)

Guidance literature:

With potassium carbonate; In water;

DOI:10.1016/j.tetasy.2009.06.019

upstream raw materials:

3-amino-3-(thiophen-2-yl)propanoic acid

ethanol

thiophene-2-carbaldehyde

hydrogen ethyl malonate

Downstream raw materials:

(S)-3-amino-3-(2-thienyl)propanoic acid

ethyl (R)-3-amino-3-(2-thienyl)propanoate

Ethyl β-[[4-[[4-(aminoiminomethyl)phenyl]amino]-1,4-dioxobutyl]amino-]-2-thiophenepropanoate

(S)-β-n-butyl-β-alanine