934622-38-5

Upstream product

• 695171-91-6 4-(tert-butyloxycarbonylamino)phenylacetaldehyde 
• 104-10-9 2-(4'-aminophenyl)ethyl alcohol 
• 104060-23-3 tert-butyl N-[4-(2-hydroxyethyl)phenyl]carbamate 
• 913239-30-2 di-(4-acetamidophenyl)-1-(benzyloxycarbonylamino)-2-(4-tert-butyloxycarbonylaminophenyl)ethanephosphonate 

Downstream Products

• 913239-59-5 di-(4-acetamidophenyl) 1-[(N-benzyloxycarbonyl-O-tert-butyl-D-seryl)-L-alanyl]amino-2-{4-[N,N'-bis(tert-butyloxycarbonyl)guanidino]phenyl}ethanephosphonate 
• 934622-42-1 di(4-acetamidophenyl) 1-amino-2-{4-[N,N'-bis(tert-butyloxycarbonyl)guanidino]phenyl}ethanephosphonate 
• 913239-31-3 di-(4-acetamidophenyl) 1-(benzyloxycarbonylamino)-2-{4-[N,N'-bis(tert-butyloxycarbonyl)guanidino]phenyl}ethanephosphonate 

Relevant academic research and scientific papers

Novel Urokinase Inhibitors

The present invention relates to novel compounds with inhibitory activity towards urokinase plasminogen activator (uPA); to methods for preparation of said uPA inhibitor compounds; to pharmaceutical compositions comprising said uPA inhibitor compounds; to

NOVEL UROKINASE INHIBITORS

The present invention relates to novel compounds with inhibitory activity towards urokinase plasminogen activator (uPA); to methods for preparation of said uPA inhibitor compounds; to pharmaceutical compositions comprising said uPA inhibitor compounds; to

Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: Optimization of the P4 position

This paper describes the structure-activity relationship in a series of tripeptidyl diphenyl phosphonate irreversible urokinase plasminogen activator (uPA) inhibitors, originally derived from an arginyltripeptide. uPA is considered an interesting target i