934660-63-6

Basic information

• Product Name: (R)-benzyl 2-aMinopropylcarbaMate
• Synonyms: (R)-benzyl 2-aMinopropylcarbaMate;N-[(2R)-2-Aminopropyl]carbamic acid phenylmethyl ester
• CAS NO: 934660-63-6
• Molecular Formula: C11H16N2O2
• Molecular Weight: 208.25694
• Mol File: 934660-63-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.107
• CAS DataBase Reference: (R)-benzyl 2-aMinopropylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-benzyl 2-aMinopropylcarbaMate(934660-63-6)
• EPA Substance Registry System: (R)-benzyl 2-aMinopropylcarbaMate(934660-63-6)

Safety Data

• Hazardous Substances Data: 934660-63-6(Hazardous Substances Data)

Usage

General Description

(R)-benzyl 2-aMinopropylcarbaMate is a chemical compound that belongs to the class of carbaMates. It is a derivative of 2-aMinopropylcarbaMate and has a benzyl group attached to the nitrogen atom. (R)-benzyl 2-aMinopropylcarbaMate has potential pharmacological activities and has been studied for its use in the treatment of conditions such as epilepsy and neurodegenerative diseases. Its specific mechanism of action and potential therapeutic applications are still being investigated. Additionally, it is important to note that the (R) in the name indicates the stereochemistry of the compound, signifying that the benzyl group is attached to the nitrogen atom in a specific orientation.

Upstream product

• 501-53-1 benzyl chloroformate 
• 78-90-0 1,2-diaminopropan 
• 78-90-0 (R)-1,2-diaminopropane 
• 28170-07-2 benzyl phenyl carbonate 
• 15967-72-3 (S)-1,2-diaminopropane 
• 1217317-62-8 (S)-benzyl tert-butyl propane-1,2-diyldicarbamate 

Downstream Products

• 1309563-15-2 C₁₅H₂₄N₂O₂ 

Relevant articles and documents

β-PNA: Peptide nucleic acid (PNA) with a chiral center at the β-position of the PNA backbone

Peptide nucleic acid (PNA) monomers with a methyl group at the β-position have been synthesized. The modified monomers were incorporated into PNA oligomers using Fmoc chemistry for solid-phase synthesis. Thermal denaturation and circular dichroism (CD) studies have shown that PNA containing the S-form monomers was well suited to form a hybrid duplex with DNA, whose stability was comparable to that of unmodified PNA-DNA duplex, whereas PNA containing the R-form monomers was not.

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

The present invention is to provide a novel compound (I), having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. Compound (I) wherein Z1 is NR4; R1 is hydrogen or lower alkyl; X is a single bond, a hetero atom group selected from O, S, SO, SO2 and NH, or lower alkylene or lower alkenylene in which the hetero atom group may intervene; R2 is optionally substituted aryl; R3 is hydrogen, a halogen, hydroxy, optionally substituted lower alkyl etc; and R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.

Selective synthesis of carbamate protected polyamines using alkyl phenyl carbonates

Utilising alkyl phenyl carbonates, an economical, practical and versatile method for selective Boc, Cbz and Alloc protection of polyamines has been developed. This method allows Boc, Cbz and Alloc protection of primary amines in the presence of secondary amines by reaction of the polyamines with the alkyl phenyl carbonates. Also, this method allows mono carbamate protection of simple symmetrical aliphatic α,ω-alkanediamines in high yields with respect to the diamine. Finally, the method allows selective carbamate protection of a primary amine located on a primary carbon in the presence of a primary amine located on a secondary or a tertiary carbon in excellent yields.