935-42-2

Basic information

• Product Name: 1-phenylcyclopropanemethylamine
• Synonyms: 1-phenylcyclopropanemethylamine;1-Phenylcyclopropanemethanamine;1-(1-phenylcyclopropyl)MethanaMine
• CAS NO: 935-42-2
• Molecular Formula: C₁₀H₁₃N
• Molecular Weight: 147.21692
• EINECS: 213-302-4
• Product Categories: Aminomethyl's;Phenyls & Phenyl-Het
• Mol File: 935-42-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 230-233 °C
• Boiling Point: 40-50℃
• Flash Point: 99.2°C
• Appearance: /
• Density: 1.047g/cm³
• Vapor Pressure: 0.0473mmHg at 25°C
• Refractive Index: 1.574
• Storage Temp.: 2-8°C
• PKA: 10.36±0.29(Predicted)
• CAS DataBase Reference: 1-phenylcyclopropanemethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylcyclopropanemethylamine(935-42-2)
• EPA Substance Registry System: 1-phenylcyclopropanemethylamine(935-42-2)

Safety Data

• Hazard Codes: C
• Statements: 22-34
• Safety Statements: 23-26-36/37/39-45
• Hazardous Substances Data: 935-42-2(Hazardous Substances Data)

Usage

General Description

1-phenylcyclopropanemethylamine is a chemical compound with a structure combining a cyclopropane ring, a phenyl group, and an amine group. It is a psychoactive substance that has been studied for its potential use in medicinal and recreational drugs. The compound is known to act as a central nervous system stimulant, affecting the levels of neurotransmitters such as dopamine and serotonin. Its effects on the brain and behavior make it potentially useful for the treatment of conditions such as depression, attention deficit hyperactivity disorder (ADHD), and anxiety. However, it also carries the risk of abuse and addiction due to its psychoactive properties. Consequently, further research and regulation are needed to determine its safety and potential therapeutic uses.

InChI:InChI=1/C10H13N/c11-8-10(6-7-10)9-4-2-1-3-5-9/h1-5H,6-8,11H2

Upstream product

• 140-29-4 phenylacetonitrile 
• 6120-96-3 1-phenyl-1-cyclopropanecarboxamide 
• 935-44-4 1-cyano-1-phenylcyclopropane 
• 106-93-4 ethylene dibromide 

Downstream Products

• 935-44-4 1-cyano-1-phenylcyclopropane 
• 21744-88-7 1-phenylcyclopropanecarbaldehyde 

Relevant articles and documents

Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst

Herein, a Grubbs-catalyzed route for the synthesis of nitriles via the aerobic oxidation of primary amines is reported. This reaction accommodates a variety of substrates, including simple primary amines, sterically hindered β,β-disubstituted amines, allylamine, benzylamines, and α-amino esters. Reaction compatibility with various functionalities is also noted, particularly with alkenes, alkynes, halogens, esters, silyl ethers, and free hydroxyl groups. The nitriles were also synthesized via the oxidation of imines generated from aldehydes and NH4OAc in situ. (Figure presented.).

CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF

The present invention is directed to cytotoxic pentapeptides, to antibody drug conjugates thereof, and to methods for using the same to treat cancer.

THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS

The invention provides compounds of formula I [INSERT CHEMICAL STRUCTURE HERE] (I) and pharmaceutically acceptable salts thereof. The formula I thiazolyl compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents and for the treatment of Alzheimer's Disease.