93504-92-8 Usage
Chemical Properties
Colorless oil
Uses
Diethyl 2-Hydroxy-3-methylbutanedioate is an intermediate used in the synthesis of 5-Methyl-2’-deoxy Cytidine-13C,15N2 (M295904), which is an isotopic analog of 5-Methyl-2’-deoxy Cytidine (M295900), a Cytidine (C998300) analog and also an isostere of Thymidine (T412000).
Check Digit Verification of cas no
The CAS Registry Mumber 93504-92-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,5,0 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 93504-92:
(7*9)+(6*3)+(5*5)+(4*0)+(3*4)+(2*9)+(1*2)=138
138 % 10 = 8
So 93504-92-8 is a valid CAS Registry Number.
93504-92-8Relevant articles and documents
Synthesis of erythro-2-Hydroxy-3-methylbutane-1,4-dioic Acid
Bhat, K. S.,Dixit, K. N.,Rao, A. S.
, p. 509 - 512 (2007/10/02)
Reduction of ethyl 3-methyl-2-oxobutane-1,4-dioate (3) with sodium borohydride furnishes a 6:1 mixture of ethyl erythro-2-hydroxy-3-methylbutane-1,4-dioate (8) and ethyl threo-2-hydroxy-3-methylbutane-1,4-dioate (18).Hydrolysis of this mixture with aq. hydrochloric acid gives a mixture of acids from which pure erythro-2-hydroxy-3-methylbutane-1,4-dioic acid (4) has been isolated.The stereochemistry of 4 has been establishrd by PMR and by transforming it to the anhydride, erythro-dihydro-3-acetyloxy-4-methyl-2,5-furandione (26).