93528-15-5

Basic information

• Product Name: Kalihinol E
• CAS NO: 93528-15-5
• Mol File: 93528-15-5.mol

Chemical Properties

• CAS DataBase Reference: Kalihinol E(CAS DataBase Reference)
• NIST Chemistry Reference: Kalihinol E(93528-15-5)
• EPA Substance Registry System: Kalihinol E(93528-15-5)

Safety Data

• Hazardous Substances Data: 93528-15-5(Hazardous Substances Data)

Upstream product

• 440333-37-9 (2S,5RS)-5-(tert-butyldimethylsilanyloxy)-2-[(2R,5S)-(5-chloro-2,6,6-trimethyltetrahydropyran-2-yl)]-6-heptenyl pivalate 
• 440333-35-7 (2S)-5-benzyloxy-2-[(2R,5S)-(5-chloro-2,6,6-trimethyltetrahydropyran-2-yl)]-pentyl pivalate 
• 440333-44-8 (E)-(R)-6-(tert-Butyl-diphenyl-silanyloxy)-3,7-dimethyl-octa-2,7-dien-1-ol 
• 440333-53-9 (2S,5RS)-5-(tert-butyldimethylsilanyloxy)-2-[(2R,5S)-(5-chloro-2,6,6-trimethyltetrahydropyran-2-yl)]-6-hepten-1-ol 
• 440333-51-7 2,2-Dimethyl-propionic acid (S)-2-((2R,5S)-5-chloro-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-5-hydroxy-hept-6-enyl ester 
• 440333-40-4 (4S,4aR,8aR)-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-methyl-3,4,4a,7,8,8a-hexahydronaphthalen-1-one 
• 440333-47-1 2,2-Dimethyl-propionic acid (S)-2-((2R,5S)-5-chloro-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-5-hydroxy-pentyl ester 
• 440333-49-3 2,2-Dimethyl-propionic acid (S)-2-((2R,5S)-5-chloro-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-5-oxo-pentyl ester 
• 252962-64-4 5,10-bisformamidokalihinol A 
• 158512-40-4 (E)-(R)-8-(tert-Butyl-dimethyl-silanyloxy)-2,6-dimethyl-octa-1,6-dien-3-ol 
• 440333-15-3 (2E,6R)-(+)-3,7-dimethyl-octa-2,7-diene-1,6-diol 
• 440333-27-7 C₄₀H₅₄O₆Si 
• 440333-58-4 (2S,3R,6R)-2-{3-(benzyloxy)propyl}-6-(tert-butyldiphenylsilyloxy)-3,7-dimethyloct-7-ene-1,3-diol 
• 440333-17-5 (2R,3R,6R)-6-(tert-butyldiphenylsilanyloxy)-2,3-epoxy-3,7-dimethyloct-7-en-1-ol 

Relevant articles and documents

Total synthesis of antimalarial diterpenoid (+)-kalihinol A

Total synthesis of antimalarial diterpenoid (+)-kalihinol A, isolated from marine sponge Acanthella sp., is achieved. This total synthesis involves regioselective alkylation of an epoxide, construction of a tetrahydropyran ring by iodo-etherification, construction of a cis-decalin ring by intramolecular Diels-Alder reaction, isomerization of cis-decalin to trans-decalin, and subsequent functionalization of the trans-decalin ring.